A splicing regulator promotes transcriptional elongation

A new study reveals that the serine/arginine-rich splicing factor SC35 is necessary to promote RNA polymerase II elongation in a subset of genes, confirming a bidirectional coupling between transcription and splicing. © 2008 Nature Publishing Group.

Guardado en:
Detalles Bibliográficos
Autores principales: Fededa, J.P., Kornblihtt, A.R.
Formato: JOUR
Materias:
arginine
messenger RNA
RNA polymerase II
serine
transcription elongation factor
alternative RNA splicing
chromatin immunoprecipitation
down regulation
enhancer region
gene expression
genetic transcription
microarray analysis
molecular recognition
nonhuman
polyadenylation
priority journal
protein domain
RNA processing
RNA sequence
RNA splicing
Schizosaccharomyces pombe
short survey
Trypanosoma cruzi
Amino Acid Motifs
Animals
Exons
Gene Expression Regulation, Fungal
Humans
Introns
Models, Biological
Nuclear Proteins
Protein Structure, Tertiary
Ribonucleoproteins
RNA Polymerase II
RNA Splicing
RNA-Binding Proteins
Transcription, Genetic
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_15459993_v15_n8_p779_Fededa
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
Descripción
Sumario:A new study reveals that the serine/arginine-rich splicing factor SC35 is necessary to promote RNA polymerase II elongation in a subset of genes, confirming a bidirectional coupling between transcription and splicing. © 2008 Nature Publishing Group.

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