A splicing regulator promotes transcriptional elongation

A new study reveals that the serine/arginine-rich splicing factor SC35 is necessary to promote RNA polymerase II elongation in a subset of genes, confirming a bidirectional coupling between transcription and splicing. © 2008 Nature Publishing Group.

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Detalles Bibliográficos
Autores principales:	Fededa, J.P., Kornblihtt, A.R.
Formato:	JOUR
Materias:	arginine messenger RNA RNA polymerase II serine transcription elongation factor alternative RNA splicing chromatin immunoprecipitation down regulation enhancer region gene expression genetic transcription microarray analysis molecular recognition nonhuman polyadenylation priority journal protein domain RNA processing RNA sequence RNA splicing Schizosaccharomyces pombe short survey Trypanosoma cruzi Amino Acid Motifs Animals Exons Gene Expression Regulation, Fungal Humans Introns Models, Biological Nuclear Proteins Protein Structure, Tertiary Ribonucleoproteins RNA Polymerase II RNA Splicing RNA-Binding Proteins Transcription, Genetic
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_15459993_v15_n8_p779_Fededa
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	todo:paper_15459993_v15_n8_p779_Fededa
record_format	dspace
spelling	todo:paper_15459993_v15_n8_p779_Fededa2023-10-03T16:23:06Z A splicing regulator promotes transcriptional elongation Fededa, J.P. Kornblihtt, A.R. arginine messenger RNA RNA polymerase II serine transcription elongation factor alternative RNA splicing chromatin immunoprecipitation down regulation enhancer region gene expression genetic transcription microarray analysis molecular recognition nonhuman polyadenylation priority journal protein domain RNA processing RNA sequence RNA splicing Schizosaccharomyces pombe short survey Trypanosoma cruzi Amino Acid Motifs Animals Exons Gene Expression Regulation, Fungal Humans Introns Models, Biological Nuclear Proteins Protein Structure, Tertiary Ribonucleoproteins RNA Polymerase II RNA Splicing RNA-Binding Proteins Transcription, Genetic A new study reveals that the serine/arginine-rich splicing factor SC35 is necessary to promote RNA polymerase II elongation in a subset of genes, confirming a bidirectional coupling between transcription and splicing. © 2008 Nature Publishing Group. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_15459993_v15_n8_p779_Fededa
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	arginine messenger RNA RNA polymerase II serine transcription elongation factor alternative RNA splicing chromatin immunoprecipitation down regulation enhancer region gene expression genetic transcription microarray analysis molecular recognition nonhuman polyadenylation priority journal protein domain RNA processing RNA sequence RNA splicing Schizosaccharomyces pombe short survey Trypanosoma cruzi Amino Acid Motifs Animals Exons Gene Expression Regulation, Fungal Humans Introns Models, Biological Nuclear Proteins Protein Structure, Tertiary Ribonucleoproteins RNA Polymerase II RNA Splicing RNA-Binding Proteins Transcription, Genetic
spellingShingle	arginine messenger RNA RNA polymerase II serine transcription elongation factor alternative RNA splicing chromatin immunoprecipitation down regulation enhancer region gene expression genetic transcription microarray analysis molecular recognition nonhuman polyadenylation priority journal protein domain RNA processing RNA sequence RNA splicing Schizosaccharomyces pombe short survey Trypanosoma cruzi Amino Acid Motifs Animals Exons Gene Expression Regulation, Fungal Humans Introns Models, Biological Nuclear Proteins Protein Structure, Tertiary Ribonucleoproteins RNA Polymerase II RNA Splicing RNA-Binding Proteins Transcription, Genetic Fededa, J.P. Kornblihtt, A.R. A splicing regulator promotes transcriptional elongation
topic_facet	arginine messenger RNA RNA polymerase II serine transcription elongation factor alternative RNA splicing chromatin immunoprecipitation down regulation enhancer region gene expression genetic transcription microarray analysis molecular recognition nonhuman polyadenylation priority journal protein domain RNA processing RNA sequence RNA splicing Schizosaccharomyces pombe short survey Trypanosoma cruzi Amino Acid Motifs Animals Exons Gene Expression Regulation, Fungal Humans Introns Models, Biological Nuclear Proteins Protein Structure, Tertiary Ribonucleoproteins RNA Polymerase II RNA Splicing RNA-Binding Proteins Transcription, Genetic
description	A new study reveals that the serine/arginine-rich splicing factor SC35 is necessary to promote RNA polymerase II elongation in a subset of genes, confirming a bidirectional coupling between transcription and splicing. © 2008 Nature Publishing Group.
format	JOUR
author	Fededa, J.P. Kornblihtt, A.R.
author_facet	Fededa, J.P. Kornblihtt, A.R.
author_sort	Fededa, J.P.
title	A splicing regulator promotes transcriptional elongation
title_short	A splicing regulator promotes transcriptional elongation
title_full	A splicing regulator promotes transcriptional elongation
title_fullStr	A splicing regulator promotes transcriptional elongation
title_full_unstemmed	A splicing regulator promotes transcriptional elongation
title_sort	splicing regulator promotes transcriptional elongation
url	http://hdl.handle.net/20.500.12110/paper_15459993_v15_n8_p779_Fededa
work_keys_str_mv	AT fededajp asplicingregulatorpromotestranscriptionalelongation AT kornblihttar asplicingregulatorpromotestranscriptionalelongation AT fededajp splicingregulatorpromotestranscriptionalelongation AT kornblihttar splicingregulatorpromotestranscriptionalelongation
_version_	1807316296400896000

A splicing regulator promotes transcriptional elongation

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