Relationship between exposure, body burden and target tissue concentration after oral administration of a low-dose mixture of pyrethroid insecticides in young adult rats

Pyrethroids (PYRs) are synthetic insecticides increasingly used in agricultural and household pest control. Little is known on how the toxicity of highly effective bolus doses of single compounds compares to more realistic scenarios of low-level exposure to PYR mixtures. In this study, we examined a...

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Detalles Bibliográficos
Autores principales: Mosquera Ortega, M.E., Romero, D.M., Pato, A.M., Sosa-Holt, C.S., Ridolfi, A., Villaamil Lepori, E., Wolansky, M.J.
Formato: JOUR
Materias:
Body temperature
Cumulative toxicity
Mixture
Pyrethroids
Rat
Toxicokinetics
bifenthrin
corn oil
cypermethrin
deltamethrin
pyrethroid
tefluthrin
unclassified drug
adult
animal experiment
animal model
animal tissue
Article
body burden
body temperature
cerebellum
controlled study
gas chromatography
lethality
liver
locomotion
neurotoxicity
nonhuman
priority journal
rat
target tissue
young adult
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_0300483X_v409_n_p53_MosqueraOrtega
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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