Genotoxic and aneugenic properties of an imidazole derivative

To contribute to a more accurate characterization of the mutagenic and aneugenic effects of thiabendazole (TBZ), a widely used antiparasitic and food preservative drug, the induction of sister chromatid exchanges (SCEs) and mitotic spindle anomalies as cytogenetic end-points were investigated. Studi...

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Detalles Bibliográficos
Autores principales: Carballo, M.A., Hick, A.S., Soloneski, S., Larramendy, M.L., Mudry, M.D.
Formato: JOUR
Materias:
Aneugen
Cell proliferation kinetics
CHO cells
Cytogenetic endpoints
Human lymphocytes
Mitotic index
Mitotic spindle disturbances
Sister chromatid exchanges
Thiabendazole
aneugen
antiparasitic agent
food preservative
imidazole derivative
tiabendazole
animal cell
article
cell proliferation
CHO cell
cytogenetics
dose response
genotoxicity
mitosis index
mitosis spindle
nonhuman
peripheral lymphocyte
priority journal
sister chromatid exchange
Aneugens
Animals
Cell Proliferation
Cell Survival
CHO Cells
Cricetinae
Cricetulus
Dose-Response Relationship, Drug
Humans
Lymphocytes
Mitotic Index
Mitotic Spindle Apparatus
Mutagenicity Tests
Sister Chromatid Exchange
Cricetulus griseus
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_0260437X_v26_n4_p293_Carballo
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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