Indole alkaloids from the tunicate Aplidium meridianum

Five new indole alkaloids, meridianins A-E (1-5), have been isolated from the tunicate Aplidium meridianum, which was collected at a depth of 100 m near the South Georgia Islands, and their structures were elucidated by spectroscopic techniques. Compounds 2-5 showed cytotoxicity toward murine tumor...

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Detalles Bibliográficos
Autores principales: Franco, L.H., De Kier Joffé, E.B., Puricelli, L., Tatian, M., Seldes, A.M., Palermo, J.A.
Formato: JOUR
Materias:
alkaloid
indole derivative
meridianin
meridianin b
meridianin c
meridianin d
meridianin e
unclassified drug
article
carbon nuclear magnetic resonance
drug cytotoxicity
drug isolation
drug structure
invertebrate
marine environment
nonhuman
proton nuclear magnetic resonance
tumor cell
Alkaloids
Animals
Antineoplastic Agents
Chromatography, High Pressure Liquid
Drug Screening Assays, Antitumor
Humans
Magnetic Resonance Spectroscopy
Mass Spectrometry
Mice
Spectrophotometry, Ultraviolet
Tumor Cells, Cultured
Urochordata
Aplidium
Aplidium meridianum
Invertebrata
Murinae
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_01633864_v61_n9_p1130_Franco
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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