Indole alkaloids from the tunicate Aplidium meridianum
Five new indole alkaloids, meridianins A-E (1-5), have been isolated from the tunicate Aplidium meridianum, which was collected at a depth of 100 m near the South Georgia Islands, and their structures were elucidated by spectroscopic techniques. Compounds 2-5 showed cytotoxicity toward murine tumor...
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_01633864_v61_n9_p1130_Franco |
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todo:paper_01633864_v61_n9_p1130_Franco2023-10-03T15:02:10Z Indole alkaloids from the tunicate Aplidium meridianum Franco, L.H. De Kier Joffé, E.B. Puricelli, L. Tatian, M. Seldes, A.M. Palermo, J.A. alkaloid indole derivative meridianin meridianin b meridianin c meridianin d meridianin e unclassified drug article carbon nuclear magnetic resonance drug cytotoxicity drug isolation drug structure invertebrate marine environment nonhuman proton nuclear magnetic resonance tumor cell Alkaloids Animals Antineoplastic Agents Chromatography, High Pressure Liquid Drug Screening Assays, Antitumor Humans Magnetic Resonance Spectroscopy Mass Spectrometry Mice Spectrophotometry, Ultraviolet Tumor Cells, Cultured Urochordata Aplidium Aplidium meridianum Invertebrata Murinae Five new indole alkaloids, meridianins A-E (1-5), have been isolated from the tunicate Aplidium meridianum, which was collected at a depth of 100 m near the South Georgia Islands, and their structures were elucidated by spectroscopic techniques. Compounds 2-5 showed cytotoxicity toward murine tumor cell lines. Fil:Puricelli, L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Seldes, A.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Palermo, J.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_01633864_v61_n9_p1130_Franco |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
alkaloid indole derivative meridianin meridianin b meridianin c meridianin d meridianin e unclassified drug article carbon nuclear magnetic resonance drug cytotoxicity drug isolation drug structure invertebrate marine environment nonhuman proton nuclear magnetic resonance tumor cell Alkaloids Animals Antineoplastic Agents Chromatography, High Pressure Liquid Drug Screening Assays, Antitumor Humans Magnetic Resonance Spectroscopy Mass Spectrometry Mice Spectrophotometry, Ultraviolet Tumor Cells, Cultured Urochordata Aplidium Aplidium meridianum Invertebrata Murinae |
| spellingShingle |
alkaloid indole derivative meridianin meridianin b meridianin c meridianin d meridianin e unclassified drug article carbon nuclear magnetic resonance drug cytotoxicity drug isolation drug structure invertebrate marine environment nonhuman proton nuclear magnetic resonance tumor cell Alkaloids Animals Antineoplastic Agents Chromatography, High Pressure Liquid Drug Screening Assays, Antitumor Humans Magnetic Resonance Spectroscopy Mass Spectrometry Mice Spectrophotometry, Ultraviolet Tumor Cells, Cultured Urochordata Aplidium Aplidium meridianum Invertebrata Murinae Franco, L.H. De Kier Joffé, E.B. Puricelli, L. Tatian, M. Seldes, A.M. Palermo, J.A. Indole alkaloids from the tunicate Aplidium meridianum |
| topic_facet |
alkaloid indole derivative meridianin meridianin b meridianin c meridianin d meridianin e unclassified drug article carbon nuclear magnetic resonance drug cytotoxicity drug isolation drug structure invertebrate marine environment nonhuman proton nuclear magnetic resonance tumor cell Alkaloids Animals Antineoplastic Agents Chromatography, High Pressure Liquid Drug Screening Assays, Antitumor Humans Magnetic Resonance Spectroscopy Mass Spectrometry Mice Spectrophotometry, Ultraviolet Tumor Cells, Cultured Urochordata Aplidium Aplidium meridianum Invertebrata Murinae |
| description |
Five new indole alkaloids, meridianins A-E (1-5), have been isolated from the tunicate Aplidium meridianum, which was collected at a depth of 100 m near the South Georgia Islands, and their structures were elucidated by spectroscopic techniques. Compounds 2-5 showed cytotoxicity toward murine tumor cell lines. |
| format |
JOUR |
| author |
Franco, L.H. De Kier Joffé, E.B. Puricelli, L. Tatian, M. Seldes, A.M. Palermo, J.A. |
| author_facet |
Franco, L.H. De Kier Joffé, E.B. Puricelli, L. Tatian, M. Seldes, A.M. Palermo, J.A. |
| author_sort |
Franco, L.H. |
| title |
Indole alkaloids from the tunicate Aplidium meridianum |
| title_short |
Indole alkaloids from the tunicate Aplidium meridianum |
| title_full |
Indole alkaloids from the tunicate Aplidium meridianum |
| title_fullStr |
Indole alkaloids from the tunicate Aplidium meridianum |
| title_full_unstemmed |
Indole alkaloids from the tunicate Aplidium meridianum |
| title_sort |
indole alkaloids from the tunicate aplidium meridianum |
| url |
http://hdl.handle.net/20.500.12110/paper_01633864_v61_n9_p1130_Franco |
| work_keys_str_mv |
AT francolh indolealkaloidsfromthetunicateaplidiummeridianum AT dekierjoffeeb indolealkaloidsfromthetunicateaplidiummeridianum AT puricellil indolealkaloidsfromthetunicateaplidiummeridianum AT tatianm indolealkaloidsfromthetunicateaplidiummeridianum AT seldesam indolealkaloidsfromthetunicateaplidiummeridianum AT palermoja indolealkaloidsfromthetunicateaplidiummeridianum |
| _version_ |
1807324296175943680 |