Spontaneous motility and prostaglandin generation in rat uterine horns isolated during the estrous cycle

Measurements were made of spontaneous contractions and release of prostaglandin E-and F-like material into the bathing medium by uterine horns isolated from rats in different stages of the sex cycle. After 70 min of contractile activity the preparations from estrous rats released more PGF than those...

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Autores principales: Franchi, A.M., Chaud, M., Borda, E.S., Gimeno, M.F., Lazzari, M.A., Gimeno, A.L.
Formato: JOUR
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Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00906980_v22_n4_p637_Franchi
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spelling todo:paper_00906980_v22_n4_p637_Franchi2023-10-03T14:54:47Z Spontaneous motility and prostaglandin generation in rat uterine horns isolated during the estrous cycle Franchi, A.M. Chaud, M. Borda, E.S. Gimeno, M.F. Lazzari, M.A. Gimeno, A.L. prostaglandin prostaglandin e prostaglandin f animal experiment estrus female genital system myometrium rat uterus horn Animals Epoprostenol Estrus Female Pregnancy Prostaglandins Prostaglandins E Prostaglandins F Rats Rats, Inbred Strains Uterine Contraction Uterus Animalia Measurements were made of spontaneous contractions and release of prostaglandin E-and F-like material into the bathing medium by uterine horns isolated from rats in different stages of the sex cycle. After 70 min of contractile activity the preparations from estrous rats released more PGF than those from proestrous or metestrous rats. On the other hand, similar amounts of PGF-like material is generated by estrous and diestrous horns. Less PGE-like material was found in the bathing solution during estrus than in metestrus or diestrus; the values obtained during proestrus were similar to those in estrus. PGI2_like material produced by chopped uterine tissue was greater during diestrus than in estrus. The initial isometric developed tension (IDT) and tension constancy varied depeding of the stage of the sex cycle. Uteri from metestrous rats exhibited greater IDT and less % change with time than preparations from estrous or proestrous rats. The initial IDT, the tension change with time and contractile frequency correlate with the PGE-like material in the bathing solution during the 4 days of the sex cycle. There was no correlation with PGF-like material. © 1979. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00906980_v22_n4_p637_Franchi
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic prostaglandin
prostaglandin e
prostaglandin f
animal experiment
estrus
female genital system
myometrium
rat
uterus horn
Animals
Epoprostenol
Estrus
Female
Pregnancy
Prostaglandins
Prostaglandins E
Prostaglandins F
Rats
Rats, Inbred Strains
Uterine Contraction
Uterus
Animalia
spellingShingle prostaglandin
prostaglandin e
prostaglandin f
animal experiment
estrus
female genital system
myometrium
rat
uterus horn
Animals
Epoprostenol
Estrus
Female
Pregnancy
Prostaglandins
Prostaglandins E
Prostaglandins F
Rats
Rats, Inbred Strains
Uterine Contraction
Uterus
Animalia
Franchi, A.M.
Chaud, M.
Borda, E.S.
Gimeno, M.F.
Lazzari, M.A.
Gimeno, A.L.
Spontaneous motility and prostaglandin generation in rat uterine horns isolated during the estrous cycle
topic_facet prostaglandin
prostaglandin e
prostaglandin f
animal experiment
estrus
female genital system
myometrium
rat
uterus horn
Animals
Epoprostenol
Estrus
Female
Pregnancy
Prostaglandins
Prostaglandins E
Prostaglandins F
Rats
Rats, Inbred Strains
Uterine Contraction
Uterus
Animalia
description Measurements were made of spontaneous contractions and release of prostaglandin E-and F-like material into the bathing medium by uterine horns isolated from rats in different stages of the sex cycle. After 70 min of contractile activity the preparations from estrous rats released more PGF than those from proestrous or metestrous rats. On the other hand, similar amounts of PGF-like material is generated by estrous and diestrous horns. Less PGE-like material was found in the bathing solution during estrus than in metestrus or diestrus; the values obtained during proestrus were similar to those in estrus. PGI2_like material produced by chopped uterine tissue was greater during diestrus than in estrus. The initial isometric developed tension (IDT) and tension constancy varied depeding of the stage of the sex cycle. Uteri from metestrous rats exhibited greater IDT and less % change with time than preparations from estrous or proestrous rats. The initial IDT, the tension change with time and contractile frequency correlate with the PGE-like material in the bathing solution during the 4 days of the sex cycle. There was no correlation with PGF-like material. © 1979.
format JOUR
author Franchi, A.M.
Chaud, M.
Borda, E.S.
Gimeno, M.F.
Lazzari, M.A.
Gimeno, A.L.
author_facet Franchi, A.M.
Chaud, M.
Borda, E.S.
Gimeno, M.F.
Lazzari, M.A.
Gimeno, A.L.
author_sort Franchi, A.M.
title Spontaneous motility and prostaglandin generation in rat uterine horns isolated during the estrous cycle
title_short Spontaneous motility and prostaglandin generation in rat uterine horns isolated during the estrous cycle
title_full Spontaneous motility and prostaglandin generation in rat uterine horns isolated during the estrous cycle
title_fullStr Spontaneous motility and prostaglandin generation in rat uterine horns isolated during the estrous cycle
title_full_unstemmed Spontaneous motility and prostaglandin generation in rat uterine horns isolated during the estrous cycle
title_sort spontaneous motility and prostaglandin generation in rat uterine horns isolated during the estrous cycle
url http://hdl.handle.net/20.500.12110/paper_00906980_v22_n4_p637_Franchi
work_keys_str_mv AT franchiam spontaneousmotilityandprostaglandingenerationinratuterinehornsisolatedduringtheestrouscycle
AT chaudm spontaneousmotilityandprostaglandingenerationinratuterinehornsisolatedduringtheestrouscycle
AT bordaes spontaneousmotilityandprostaglandingenerationinratuterinehornsisolatedduringtheestrouscycle
AT gimenomf spontaneousmotilityandprostaglandingenerationinratuterinehornsisolatedduringtheestrouscycle
AT lazzarima spontaneousmotilityandprostaglandingenerationinratuterinehornsisolatedduringtheestrouscycle
AT gimenoal spontaneousmotilityandprostaglandingenerationinratuterinehornsisolatedduringtheestrouscycle
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