Spontaneous motility and prostaglandin generation in rat uterine horns isolated during the estrous cycle
Measurements were made of spontaneous contractions and release of prostaglandin E-and F-like material into the bathing medium by uterine horns isolated from rats in different stages of the sex cycle. After 70 min of contractile activity the preparations from estrous rats released more PGF than those...
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todo:paper_00906980_v22_n4_p637_Franchi2023-10-03T14:54:47Z Spontaneous motility and prostaglandin generation in rat uterine horns isolated during the estrous cycle Franchi, A.M. Chaud, M. Borda, E.S. Gimeno, M.F. Lazzari, M.A. Gimeno, A.L. prostaglandin prostaglandin e prostaglandin f animal experiment estrus female genital system myometrium rat uterus horn Animals Epoprostenol Estrus Female Pregnancy Prostaglandins Prostaglandins E Prostaglandins F Rats Rats, Inbred Strains Uterine Contraction Uterus Animalia Measurements were made of spontaneous contractions and release of prostaglandin E-and F-like material into the bathing medium by uterine horns isolated from rats in different stages of the sex cycle. After 70 min of contractile activity the preparations from estrous rats released more PGF than those from proestrous or metestrous rats. On the other hand, similar amounts of PGF-like material is generated by estrous and diestrous horns. Less PGE-like material was found in the bathing solution during estrus than in metestrus or diestrus; the values obtained during proestrus were similar to those in estrus. PGI2_like material produced by chopped uterine tissue was greater during diestrus than in estrus. The initial isometric developed tension (IDT) and tension constancy varied depeding of the stage of the sex cycle. Uteri from metestrous rats exhibited greater IDT and less % change with time than preparations from estrous or proestrous rats. The initial IDT, the tension change with time and contractile frequency correlate with the PGE-like material in the bathing solution during the 4 days of the sex cycle. There was no correlation with PGF-like material. © 1979. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00906980_v22_n4_p637_Franchi |
institution |
Universidad de Buenos Aires |
institution_str |
I-28 |
repository_str |
R-134 |
collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
topic |
prostaglandin prostaglandin e prostaglandin f animal experiment estrus female genital system myometrium rat uterus horn Animals Epoprostenol Estrus Female Pregnancy Prostaglandins Prostaglandins E Prostaglandins F Rats Rats, Inbred Strains Uterine Contraction Uterus Animalia |
spellingShingle |
prostaglandin prostaglandin e prostaglandin f animal experiment estrus female genital system myometrium rat uterus horn Animals Epoprostenol Estrus Female Pregnancy Prostaglandins Prostaglandins E Prostaglandins F Rats Rats, Inbred Strains Uterine Contraction Uterus Animalia Franchi, A.M. Chaud, M. Borda, E.S. Gimeno, M.F. Lazzari, M.A. Gimeno, A.L. Spontaneous motility and prostaglandin generation in rat uterine horns isolated during the estrous cycle |
topic_facet |
prostaglandin prostaglandin e prostaglandin f animal experiment estrus female genital system myometrium rat uterus horn Animals Epoprostenol Estrus Female Pregnancy Prostaglandins Prostaglandins E Prostaglandins F Rats Rats, Inbred Strains Uterine Contraction Uterus Animalia |
description |
Measurements were made of spontaneous contractions and release of prostaglandin E-and F-like material into the bathing medium by uterine horns isolated from rats in different stages of the sex cycle. After 70 min of contractile activity the preparations from estrous rats released more PGF than those from proestrous or metestrous rats. On the other hand, similar amounts of PGF-like material is generated by estrous and diestrous horns. Less PGE-like material was found in the bathing solution during estrus than in metestrus or diestrus; the values obtained during proestrus were similar to those in estrus. PGI2_like material produced by chopped uterine tissue was greater during diestrus than in estrus. The initial isometric developed tension (IDT) and tension constancy varied depeding of the stage of the sex cycle. Uteri from metestrous rats exhibited greater IDT and less % change with time than preparations from estrous or proestrous rats. The initial IDT, the tension change with time and contractile frequency correlate with the PGE-like material in the bathing solution during the 4 days of the sex cycle. There was no correlation with PGF-like material. © 1979. |
format |
JOUR |
author |
Franchi, A.M. Chaud, M. Borda, E.S. Gimeno, M.F. Lazzari, M.A. Gimeno, A.L. |
author_facet |
Franchi, A.M. Chaud, M. Borda, E.S. Gimeno, M.F. Lazzari, M.A. Gimeno, A.L. |
author_sort |
Franchi, A.M. |
title |
Spontaneous motility and prostaglandin generation in rat uterine horns isolated during the estrous cycle |
title_short |
Spontaneous motility and prostaglandin generation in rat uterine horns isolated during the estrous cycle |
title_full |
Spontaneous motility and prostaglandin generation in rat uterine horns isolated during the estrous cycle |
title_fullStr |
Spontaneous motility and prostaglandin generation in rat uterine horns isolated during the estrous cycle |
title_full_unstemmed |
Spontaneous motility and prostaglandin generation in rat uterine horns isolated during the estrous cycle |
title_sort |
spontaneous motility and prostaglandin generation in rat uterine horns isolated during the estrous cycle |
url |
http://hdl.handle.net/20.500.12110/paper_00906980_v22_n4_p637_Franchi |
work_keys_str_mv |
AT franchiam spontaneousmotilityandprostaglandingenerationinratuterinehornsisolatedduringtheestrouscycle AT chaudm spontaneousmotilityandprostaglandingenerationinratuterinehornsisolatedduringtheestrouscycle AT bordaes spontaneousmotilityandprostaglandingenerationinratuterinehornsisolatedduringtheestrouscycle AT gimenomf spontaneousmotilityandprostaglandingenerationinratuterinehornsisolatedduringtheestrouscycle AT lazzarima spontaneousmotilityandprostaglandingenerationinratuterinehornsisolatedduringtheestrouscycle AT gimenoal spontaneousmotilityandprostaglandingenerationinratuterinehornsisolatedduringtheestrouscycle |
_version_ |
1807319855390523392 |