Effect of pentoxifylline and aminophylline on biogenic amine metabolism of the rat brain

In the brain of rats injected with pentoxifylline [3,7-dimethyl-1(5-oxo-hexyl)-xanthine] or aminophylline the following was observed: (i) dose-dependent increases of tryptophan and 5-droxyindoleacetic acid levels and of 5-hydroxytryptophan and dihydroxyphenylalanine accumulation after treatment with...

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Detalles Bibliográficos
Autor principal:	Cardinali, D.P.
Formato:	JOUR
Materias:	5-Hydroxyindoleacetic acid Aminophylline Catecholamine turnover Methylxanthines Tryptophan and tyrosine hydroxylation 5 hydroxyindoleacetic acid 5 hydroxytryptophan amine aminophylline benserazide catecholamine dopa metirosine pargyline pentoxifylline serotonin tryptophan tryptophan hydroxylase tyrosine 3 monooxygenase animal experiment brain catecholamine brain level catecholamine metabolism central nervous system column chromatography controlled study dose response dose time effect relation double blind procedure drug analysis drug comparison drug efficacy drug response in vitro study intraperitoneal drug administration methodology rat Animal Biogenic Amines Brain Dopamine Male Norepinephrine Pentoxifylline Rats Serotonin Theobromine
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00142999_v47_n2_p239_Cardinali
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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