Effect of stress on hepatic 11β-hydroxysteroid dehydrogenase activity and its influence on carbohydrate metabolism

Stress activates the synthesis and secretion of catecholamines and adrenal glucocorticoids, increasing their circulating levels. In vivo, hepatic 11β-hydroxysteroid dehydrogenase 1 (HSD1) stimulates the shift of 11-dehydrocorticosterone to corticosterone, enhancing active glucocorticoids at tissue l...

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Detalles Bibliográficos
Autores principales: Altuna, M.E., Lelli, S.M., San Martín De Viale, L.C., Damasco, M.C.
Formato: JOUR
Materias:
Carbohydrate metabolism
Glucocorticoids
Hepatic HSD1
PEPCK
Rat
Stress
11beta hydroxysteroid dehydrogenase 1
corticosterone
dehydrocorticosterone
glucocorticoid
glycogen
hydrochloric acid
oxidoreductase
phosphoenolpyruvate carboxykinase (GTP)
sodium chloride
unclassified drug
animal experiment
article
cannula
carbohydrate metabolism
controlled study
enzyme activity
enzyme kinetics
gluconeogenesis
glucose blood level
male
metabolic acidosis
nonhuman
priority journal
rat
stress
11-beta-Hydroxysteroid Dehydrogenase Type 1
11-beta-Hydroxysteroid Dehydrogenases
Animals
Blood Glucose
Carbohydrate Metabolism
Corticosterone
Cytosol
Gluconeogenesis
Kinetics
Liver
Liver Glycogen
Male
Microsomes, Liver
Phosphoenolpyruvate Carboxykinase (ATP)
Rats
Rats, Sprague-Dawley
Stress, Psychological
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00084212_v84_n10_p977_Altuna
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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