Cellular inactivation and antitumor efficacy of a new zinc phthalocyanine with potential use in photodynamic therapy

The aim of the present study was to evaluate the photodynamic efficacy of a novel phthalocyanine derivate 2,3,9,10,16,17,23,24-octakis[(N,N-dimethylamino) ethylsulfanyl]phthalocyaninatozinc(II) (referred here as S1) using MCF-7c3 human breast cancer cells and the LM2 adenocarcinoma subcutaneously im...

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Detalles Bibliográficos
Publicado:	2008
Materias:	Apoptosis Cancer Necrosis Photodynamic Therapy Photosensitizer dimyristoylphosphatidylcholine liposome phthalocyanine zinc adenocarcinoma animal cell animal model animal tissue antineoplastic activity apoptosis article breast cancer cancer cell culture cancer inhibition cell activation cell damage controlled study cytolysis drug delivery system drug distribution female human human cell incubation time internalization light damage light irradiance lysosome microscopy mitochondrion morphology mouse nonhuman photodynamic therapy photodynamics treatment response tumor volume Animals Cell Death Cell Line, Tumor Cell Survival Culture Media Darkness Female Humans Indoles Intracellular Space Mice Mice, Inbred BALB C Neoplasms Organometallic Compounds Photochemotherapy Solutions Spectrometry, Fluorescence Treatment Outcome Xenograft Model Antitumor Assays Animalia Mus
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_13572725_v40_n10_p2192_Vittar http://hdl.handle.net/20.500.12110/paper_13572725_v40_n10_p2192_Vittar
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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