Programmed cell death and differential JNK, p38 and ERK response in a prenatal acute hypoxic hypoxia model

We previously found that prenatal hypoxia induces a significant increase in the levels of active Caspase 3 at 60 min post-hypoxia (p-h) and in the number of TUNEL-positive pyknotic cells, which peaks at 6 h p-h. The aim of this work was to study alterations in MAPKs pathways and the effect of specif...

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Guardado en:
Detalles Bibliográficos
Autores principales: Vacotto, Marina, Coso, Omar Adrian
Publicado: 2008
Materias:
Chick optic lobe
CNS development
Hypoxia
MAPKs
Programmed cell death
4 (4 fluorophenyl) 2 (4 methylsulfinylphenyl) 5 (4 pyridyl)imidazole
anthra[1,9 cd]pyrazol 6(2h) one
caspase 3
mitogen activated protein kinase 1
mitogen activated protein kinase 3
mitogen activated protein kinase p38
stress activated protein kinase
acute disease
animal cell
apoptosis
article
brain development
brain hypoxia
cell differentiation
controlled study
dose response
drug inhibition
embryo development
nick end labeling
nonhuman
optic lobe
prenatal period
priority journal
protein expression
Western blotting
Animals
Apoptosis
Blotting, Western
Caspase 3
Chick Embryo
Dose-Response Relationship, Drug
Enzyme Inhibitors
Extracellular Signal-Regulated MAP Kinases
Fetal Hypoxia
In Situ Nick-End Labeling
JNK Mitogen-Activated Protein Kinases
p38 Mitogen-Activated Protein Kinases
Signal Transduction
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01970186_v52_n4-5_p857_Vacotto
http://hdl.handle.net/20.500.12110/paper_01970186_v52_n4-5_p857_Vacotto
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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