Whole seeds of Bauhinia variegata L. (Fabaceae) as an efficient biocatalyst for benzyl alcohol preparations from benzaldehydes

Whole seeds of Bauhinia variegata L. (Fabaceae) were utilized as a biological reducer to transform benzaldehyde into benzyl alcohol. The effects of some variables such as temperature, the load of substrate and co-solvent, were established to optimize the reductive process. Utilizing the optimal reac...

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Detalles Bibliográficos
Autores principales: Demmel, Gabriela Inés, Bordón, Daniela L., Vázquez, Ana María, Decarlini, María Florencia, Díaz Panero, Mariángeles, Rossi, Laura I., Aimar, Mario Leandro
Formato: Artículo
Lenguaje:Español
Publicado: Taylor and Francis Ltd. 2021
Materias:
QD Química
Acceso en línea:http://pa.bibdigital.ucc.edu.ar/3320/1/A_Demmel_Bordon_Vazquez.pdf
Aporte de:
Producción Académica Universidad Católica de Córdoba (UCCor) de Universidad Católica de Córdoba
id I38-R144-3320
record_format dspace
institution Universidad Católica de Córdoba
institution_str I-38
repository_str R-144
collection Producción Académica Universidad Católica de Córdoba (UCCor)
language Español
orig_language_str_mv spa
topic QD Química
spellingShingle QD Química
Demmel, Gabriela Inés
Bordón, Daniela L.
Vázquez, Ana María
Decarlini, María Florencia
Díaz Panero, Mariángeles
Rossi, Laura I.
Aimar, Mario Leandro
Whole seeds of Bauhinia variegata L. (Fabaceae) as an efficient biocatalyst for benzyl alcohol preparations from benzaldehydes
topic_facet QD Química
description Whole seeds of Bauhinia variegata L. (Fabaceae) were utilized as a biological reducer to transform benzaldehyde into benzyl alcohol. The effects of some variables such as temperature, the load of substrate and co-solvent, were established to optimize the reductive process. Utilizing the optimal reaction conditions, a laboratory-scale reaction (final concentration of the substrate: 21.2 mM) was performed to obtain benzyl alcohol (conversion: 95%; isolated yield: 49%; productivity: 1.11 g L−1 or 0.046 g L−1h−1 of benzyl alcohol). In addition, using these optimal conditions, fourteen substituted benzaldehydes were reduced, with a conversion achieved to their corresponding benzyl alcohols ranging from 62% to >99% (isolated yields from 7% to 70%). Moreover, useful building blocks by the synthesis of the drugs and important commercial products were also obtained. The scope, limitations and advantages of this new biocatalytic synthetic method are also discussed.
format Artículo
Artículo
author Demmel, Gabriela Inés
Bordón, Daniela L.
Vázquez, Ana María
Decarlini, María Florencia
Díaz Panero, Mariángeles
Rossi, Laura I.
Aimar, Mario Leandro
author_facet Demmel, Gabriela Inés
Bordón, Daniela L.
Vázquez, Ana María
Decarlini, María Florencia
Díaz Panero, Mariángeles
Rossi, Laura I.
Aimar, Mario Leandro
author_sort Demmel, Gabriela Inés
title Whole seeds of Bauhinia variegata L. (Fabaceae) as an efficient biocatalyst for benzyl alcohol preparations from benzaldehydes
title_short Whole seeds of Bauhinia variegata L. (Fabaceae) as an efficient biocatalyst for benzyl alcohol preparations from benzaldehydes
title_full Whole seeds of Bauhinia variegata L. (Fabaceae) as an efficient biocatalyst for benzyl alcohol preparations from benzaldehydes
title_fullStr Whole seeds of Bauhinia variegata L. (Fabaceae) as an efficient biocatalyst for benzyl alcohol preparations from benzaldehydes
title_full_unstemmed Whole seeds of Bauhinia variegata L. (Fabaceae) as an efficient biocatalyst for benzyl alcohol preparations from benzaldehydes
title_sort whole seeds of bauhinia variegata l. (fabaceae) as an efficient biocatalyst for benzyl alcohol preparations from benzaldehydes
publisher Taylor and Francis Ltd.
publishDate 2021
url http://pa.bibdigital.ucc.edu.ar/3320/1/A_Demmel_Bordon_Vazquez.pdf
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