Type-Specific Identification of Genital Human Papillomavirus Infection in Women with Cytological Abnormality

Objectives: To estimate the frequency of human papillomavirus (HPV) infection and the genotype distribution of HPV among women with a Pap smear showing atypical squamous cells of undetermined significance (ASC-US) attending the Program for the Detection and Control of Cervical Cancer in Bogotá, Colo...

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Autores principales:	Vargas, H., Sánchez, J. P., Guerrero, M. L., Ortiz, L.T., Rodríguez, D. M., Amaya, J., Diaz, L. P., Gómez, S. L., Golijow, Carlos Daniel
Formato:	Articulo
Lenguaje:	Inglés
Publicado:	2016
Materias:	Ciencias Médicas Atypical squamous cells of undetermined significance Cervical cancer Cytological abnormality Epidemiological profile Human papillomavirus Prevalence
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/85912
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

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record_format	dspace
institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Ciencias Médicas Atypical squamous cells of undetermined significance Cervical cancer Cytological abnormality Epidemiological profile Human papillomavirus Prevalence
spellingShingle	Ciencias Médicas Atypical squamous cells of undetermined significance Cervical cancer Cytological abnormality Epidemiological profile Human papillomavirus Prevalence Vargas, H. Sánchez, J. P. Guerrero, M. L. Ortiz, L.T. Rodríguez, D. M. Amaya, J. Diaz, L. P. Gómez, S. L. Golijow, Carlos Daniel Type-Specific Identification of Genital Human Papillomavirus Infection in Women with Cytological Abnormality
topic_facet	Ciencias Médicas Atypical squamous cells of undetermined significance Cervical cancer Cytological abnormality Epidemiological profile Human papillomavirus Prevalence
description	Objectives: To estimate the frequency of human papillomavirus (HPV) infection and the genotype distribution of HPV among women with a Pap smear showing atypical squamous cells of undetermined significance (ASC-US) attending the Program for the Detection and Control of Cervical Cancer in Bogotá, Colombia. Study Design: Cervical samples from 200 women with an ASC-US Pap smear were analyzed for the presence of HPV DNA and genotype distribution using a commercial molecular technique (Linear Array®; Roche Molecular Systems, USA). Results: HPV infection was found in 140 women (70%). High-risk HPV types were present in 46.4% of the samples; 16.4% showed a low-risk HPV type, and 37.1% showed both. Of the positive samples, 42.9% were infected with a single viral genotype, whereas 57.1% exhibited multiple HPV infections. The most common HPV genotypes were HPV 16, 53, and 52 with a prevalence of 26.4, 16.4, and 13.6%, respectively. Conclusion: The epidemiological characterization of HPV infections described in this study might guide actions for epidemiological surveillance to strengthen the program in Bogotá and to develop appropriate HPV vaccination programs.
format	Articulo Articulo
author	Vargas, H. Sánchez, J. P. Guerrero, M. L. Ortiz, L.T. Rodríguez, D. M. Amaya, J. Diaz, L. P. Gómez, S. L. Golijow, Carlos Daniel
author_facet	Vargas, H. Sánchez, J. P. Guerrero, M. L. Ortiz, L.T. Rodríguez, D. M. Amaya, J. Diaz, L. P. Gómez, S. L. Golijow, Carlos Daniel
author_sort	Vargas, H.
title	Type-Specific Identification of Genital Human Papillomavirus Infection in Women with Cytological Abnormality
title_short	Type-Specific Identification of Genital Human Papillomavirus Infection in Women with Cytological Abnormality
title_full	Type-Specific Identification of Genital Human Papillomavirus Infection in Women with Cytological Abnormality
title_fullStr	Type-Specific Identification of Genital Human Papillomavirus Infection in Women with Cytological Abnormality
title_full_unstemmed	Type-Specific Identification of Genital Human Papillomavirus Infection in Women with Cytological Abnormality
title_sort	type-specific identification of genital human papillomavirus infection in women with cytological abnormality
publishDate	2016
url	http://sedici.unlp.edu.ar/handle/10915/85912
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Type-Specific Identification of Genital Human Papillomavirus Infection in Women with Cytological Abnormality

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