Characterization of the bovine gene LIPE and possible influence on fatty acid composition of meat

LIPE is an intracellular neutral lipase, which is capable of hydrolyzing a variety of esters and plays a key role in the mobilization of fatty acids from diacylglycerols. The objectives of this study were to characterize the genetic polymorphism of bovine LIPE gene and to evaluate the possible assoc...

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Detalles Bibliográficos
Autores principales: Goszczynski, Daniel Estanislao, Papaleo Mazzucco, Juliana, Ripoli, María Verónica, Villarreal, Edgardo Leopoldo, Rogberg Muñoz, Andrés, Mezzadra, Carlos Alberto, Melucci, Lilia Magdalena, Giovambattista, Guillermo
Formato: Articulo
Lenguaje:Inglés
Publicado: 2014
Materias:
Ciencias Veterinarias
Bovine
LIPE
Lipid content
Polymorphism
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/85420
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-85420
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Veterinarias
Bovine
LIPE
Lipid content
Polymorphism
spellingShingle Ciencias Veterinarias
Bovine
LIPE
Lipid content
Polymorphism
Goszczynski, Daniel Estanislao
Papaleo Mazzucco, Juliana
Ripoli, María Verónica
Villarreal, Edgardo Leopoldo
Rogberg Muñoz, Andrés
Mezzadra, Carlos Alberto
Melucci, Lilia Magdalena
Giovambattista, Guillermo
Characterization of the bovine gene LIPE and possible influence on fatty acid composition of meat
topic_facet Ciencias Veterinarias
Bovine
LIPE
Lipid content
Polymorphism
description LIPE is an intracellular neutral lipase, which is capable of hydrolyzing a variety of esters and plays a key role in the mobilization of fatty acids from diacylglycerols. The objectives of this study were to characterize the genetic polymorphism of bovine LIPE gene and to evaluate the possible association between three SNPs in the coding regions of this gene with the fatty acid composition of meat in a cattle population. Forty-three unrelated animals from different cattle breeds were re-sequenced and 21 SNPs were detected over approximately 2600. bp, five of these SNPs were novel. Three SNPs were selected, on the basis of evolutionary conservation, to perform validation and association studies in a crossbred cattle population. Our results may suggest a possible association of SNP1 with contents of oleic acid and total monounsaturated fatty acids (p < 0.01), and SNP2 and SNP3 with Heneicosylic acid content (p < 0.01), may be helpful to improve the quality of meat and improve health.
format Articulo
Articulo
author Goszczynski, Daniel Estanislao
Papaleo Mazzucco, Juliana
Ripoli, María Verónica
Villarreal, Edgardo Leopoldo
Rogberg Muñoz, Andrés
Mezzadra, Carlos Alberto
Melucci, Lilia Magdalena
Giovambattista, Guillermo
author_facet Goszczynski, Daniel Estanislao
Papaleo Mazzucco, Juliana
Ripoli, María Verónica
Villarreal, Edgardo Leopoldo
Rogberg Muñoz, Andrés
Mezzadra, Carlos Alberto
Melucci, Lilia Magdalena
Giovambattista, Guillermo
author_sort Goszczynski, Daniel Estanislao
title Characterization of the bovine gene LIPE and possible influence on fatty acid composition of meat
title_short Characterization of the bovine gene LIPE and possible influence on fatty acid composition of meat
title_full Characterization of the bovine gene LIPE and possible influence on fatty acid composition of meat
title_fullStr Characterization of the bovine gene LIPE and possible influence on fatty acid composition of meat
title_full_unstemmed Characterization of the bovine gene LIPE and possible influence on fatty acid composition of meat
title_sort characterization of the bovine gene lipe and possible influence on fatty acid composition of meat
publishDate 2014
url http://sedici.unlp.edu.ar/handle/10915/85420
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