Micronuclei induction in Rana catesbeiana tadpoles by the pyrethroid insecticide lambda-cyhalothrin

Pyrethroid lambda-cyhalothrin genotoxicity was evaluated using the micronucleus test in Rana catesbeiana tadpoles. The effects of concentration and exposure time on the micronuclei frequency were studied in blood smears obtained from tadpoles exposed to four concentrations (0.02, 0.1, 0.2 and 0.4 μg...

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Detalles Bibliográficos
Autores principales: Campana, Marcela Alejandra, Panzeri, Ana María, Moreno, Victor Jorge, Dulout, Fernando Noel
Formato: Articulo Revision
Lenguaje:Inglés
Publicado: 2003
Materias:
Ciencias Veterinarias
Genotoxicity
Lambda-cyhalothrin
Micronucleus test
Tadpoles
Rana catesbeiana
Genotoxicidad
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/84839
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-84839
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Veterinarias
Genotoxicity
Lambda-cyhalothrin
Micronucleus test
Tadpoles
Rana catesbeiana
Genotoxicidad
spellingShingle Ciencias Veterinarias
Genotoxicity
Lambda-cyhalothrin
Micronucleus test
Tadpoles
Rana catesbeiana
Genotoxicidad
Campana, Marcela Alejandra
Panzeri, Ana María
Moreno, Victor Jorge
Dulout, Fernando Noel
Micronuclei induction in Rana catesbeiana tadpoles by the pyrethroid insecticide lambda-cyhalothrin
topic_facet Ciencias Veterinarias
Genotoxicity
Lambda-cyhalothrin
Micronucleus test
Tadpoles
Rana catesbeiana
Genotoxicidad
description Pyrethroid lambda-cyhalothrin genotoxicity was evaluated using the micronucleus test in Rana catesbeiana tadpoles. The effects of concentration and exposure time on the micronuclei frequency were studied in blood smears obtained from tadpoles exposed to four concentrations (0.02, 0.1, 0.2 and 0.4 μg/L) of the compound for 24, 48, 72 and 96 h and 8, 15, 20 and 30 days. As a positive control, tadpoles were exposed to cyclophosphamide (5 mg/L). The micronucleated cell frequency was expressed per 1,000 cells. R. catesbeiana tadpoles exposed to increasing concentrations of lambda-cyhalothrin showed an increase in the micronuclei frequency in peripheral blood. Tadpoles exposed to cyclophosphamide (CP) also showed a significant increase in micronucleated erythrocytes which peaked after 15 days. These results suggest that R. catesbeiana tadpoles may provide a useful model for monitoring water pollution.
format Articulo
Revision
author Campana, Marcela Alejandra
Panzeri, Ana María
Moreno, Victor Jorge
Dulout, Fernando Noel
author_facet Campana, Marcela Alejandra
Panzeri, Ana María
Moreno, Victor Jorge
Dulout, Fernando Noel
author_sort Campana, Marcela Alejandra
title Micronuclei induction in Rana catesbeiana tadpoles by the pyrethroid insecticide lambda-cyhalothrin
title_short Micronuclei induction in Rana catesbeiana tadpoles by the pyrethroid insecticide lambda-cyhalothrin
title_full Micronuclei induction in Rana catesbeiana tadpoles by the pyrethroid insecticide lambda-cyhalothrin
title_fullStr Micronuclei induction in Rana catesbeiana tadpoles by the pyrethroid insecticide lambda-cyhalothrin
title_full_unstemmed Micronuclei induction in Rana catesbeiana tadpoles by the pyrethroid insecticide lambda-cyhalothrin
title_sort micronuclei induction in rana catesbeiana tadpoles by the pyrethroid insecticide lambda-cyhalothrin
publishDate 2003
url http://sedici.unlp.edu.ar/handle/10915/84839
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