Anti HSV-1 activity of five strawberry cultivars

Five strawberry (Fragaria x ananassa) cultivars harvested in Passo Fundo (State of Rio Grande do Sul, Brazil) were quantified for their total flavonoids (TF) and total anthocyanins contents (TA) and the extracts were evaluated for their in vitro antiherpes (anti-HSV-1, KOS strain) activity. The cult...

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Detalles Bibliográficos
Autores principales: Simões, Cláudia Maria Oliveira, Reginatto, Flávio Henrique, Calvete, Eunice, Blum Silva, Carlos H., Carvalho, Annelise
Formato: Articulo
Lenguaje:Inglés
Publicado: 2012
Materias:
Farmacia
Herpes Simple
Fragaria
Flavonoides
Agentes Antivirales
Antocianinas
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8440
http://www.latamjpharm.org/resumenes/31/1/LAJOP_31_1_1_20.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-8440
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
Herpes Simple
Fragaria
Flavonoides
Agentes Antivirales
Antocianinas
spellingShingle Farmacia
Herpes Simple
Fragaria
Flavonoides
Agentes Antivirales
Antocianinas
Simões, Cláudia Maria Oliveira
Reginatto, Flávio Henrique
Calvete, Eunice
Blum Silva, Carlos H.
Carvalho, Annelise
Anti HSV-1 activity of five strawberry cultivars
topic_facet Farmacia
Herpes Simple
Fragaria
Flavonoides
Agentes Antivirales
Antocianinas
description Five strawberry (Fragaria x ananassa) cultivars harvested in Passo Fundo (State of Rio Grande do Sul, Brazil) were quantified for their total flavonoids (TF) and total anthocyanins contents (TA) and the extracts were evaluated for their in vitro antiherpes (anti-HSV-1, KOS strain) activity. The cultivars Camarosa and Aromas presented the highest TF (149.1 and 129.4 mg RE/100g FF), respectively; and TA (92.8 and 84.4 mg CGE/100 g FF), respectively. On the other hand, Camino Real cultivar showed the lowest TF (69.9 mg RE/100 g FF) and TA (46.2 mg CGE/100 g FF). With regard to the antiherpes activity, Camarosa and Aromas cultivars also displayed the highest activity detected (IC50 = 1.68 mg/mL and 1.80 mg/mL, respectively) and Camino Real the lowest (IC50 = 2.69 mg/mL). A relationship between the presence of flavonoids and anthocyanins and the detected anti-HSV-1 activity might be suggested for the strawberry cultivars studied.
format Articulo
Articulo
author Simões, Cláudia Maria Oliveira
Reginatto, Flávio Henrique
Calvete, Eunice
Blum Silva, Carlos H.
Carvalho, Annelise
author_facet Simões, Cláudia Maria Oliveira
Reginatto, Flávio Henrique
Calvete, Eunice
Blum Silva, Carlos H.
Carvalho, Annelise
author_sort Simões, Cláudia Maria Oliveira
title Anti HSV-1 activity of five strawberry cultivars
title_short Anti HSV-1 activity of five strawberry cultivars
title_full Anti HSV-1 activity of five strawberry cultivars
title_fullStr Anti HSV-1 activity of five strawberry cultivars
title_full_unstemmed Anti HSV-1 activity of five strawberry cultivars
title_sort anti hsv-1 activity of five strawberry cultivars
publishDate 2012
url http://sedici.unlp.edu.ar/handle/10915/8440
http://www.latamjpharm.org/resumenes/31/1/LAJOP_31_1_1_20.pdf
work_keys_str_mv AT simoesclaudiamariaoliveira antihsv1activityoffivestrawberrycultivars
AT reginattoflaviohenrique antihsv1activityoffivestrawberrycultivars
AT calveteeunice antihsv1activityoffivestrawberrycultivars
AT blumsilvacarlosh antihsv1activityoffivestrawberrycultivars
AT carvalhoannelise antihsv1activityoffivestrawberrycultivars
bdutipo_str Repositorios
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