Rapid and global identification of potentially bioactive Crude Eextracts from chinese medicinal formula Chuanbeipipa dropping pills

A dichloromethane extract (DME) of the traditional Chinese medicine Chuanbeipipa dropping pill (CBPP) was obtained. The main bioactive components of the DME were identified and analysed by ultra-performance liquid chromatography/electrospray ionisation quadrupole time-of-flight tandem mass spectrome...

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Autores principales: Guo, Yanhong, Wang, Jing, Bai, Gang, Hou, Yuan-Yuan, Cheng, Bin-Feng, Cao, Xuelin, Zhang, Yun-hui, Dong, Lin-Yi
Formato: Articulo
Lenguaje:Inglés
Publicado: 2012
Materias:
Farmacia
Extractos Vegetales
active composition; Chuanbeipipa dropping pills; crude extracts; UPLC-Q-TOF
Cromatografía Liquida
Medicina China Tradicional
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8423
http://www.latamjpharm.org/resumenes/31/1/LAJOP_31_1_1_3.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-8423
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
Extractos Vegetales
active composition; Chuanbeipipa dropping pills; crude extracts; UPLC-Q-TOF
Cromatografía Liquida
Medicina China Tradicional
spellingShingle Farmacia
Extractos Vegetales
active composition; Chuanbeipipa dropping pills; crude extracts; UPLC-Q-TOF
Cromatografía Liquida
Medicina China Tradicional
Guo, Yanhong
Wang, Jing
Bai, Gang
Hou, Yuan-Yuan
Cheng, Bin-Feng
Cao, Xuelin
Zhang, Yun-hui
Dong, Lin-Yi
Rapid and global identification of potentially bioactive Crude Eextracts from chinese medicinal formula Chuanbeipipa dropping pills
topic_facet Farmacia
Extractos Vegetales
active composition; Chuanbeipipa dropping pills; crude extracts; UPLC-Q-TOF
Cromatografía Liquida
Medicina China Tradicional
description A dichloromethane extract (DME) of the traditional Chinese medicine Chuanbeipipa dropping pill (CBPP) was obtained. The main bioactive components of the DME were identified and analysed by ultra-performance liquid chromatography/electrospray ionisation quadrupole time-of-flight tandem mass spectrometry. The retention time, mass spectrum, and tandem mass spectrum of the DME were compared with those of reference standards as well as literature data, and fifty-five components were resolved. Fourteen components were confirmed to have effects on cough and asthma. The current study aimed to establish a reliable and effective method for screening the potentially bioactive components of CBPP, report for the first time the basis of CBPP pharmacology, and provide useful information for further studies on the CBPP mechanism of action.
format Articulo
Articulo
author Guo, Yanhong
Wang, Jing
Bai, Gang
Hou, Yuan-Yuan
Cheng, Bin-Feng
Cao, Xuelin
Zhang, Yun-hui
Dong, Lin-Yi
author_facet Guo, Yanhong
Wang, Jing
Bai, Gang
Hou, Yuan-Yuan
Cheng, Bin-Feng
Cao, Xuelin
Zhang, Yun-hui
Dong, Lin-Yi
author_sort Guo, Yanhong
title Rapid and global identification of potentially bioactive Crude Eextracts from chinese medicinal formula Chuanbeipipa dropping pills
title_short Rapid and global identification of potentially bioactive Crude Eextracts from chinese medicinal formula Chuanbeipipa dropping pills
title_full Rapid and global identification of potentially bioactive Crude Eextracts from chinese medicinal formula Chuanbeipipa dropping pills
title_fullStr Rapid and global identification of potentially bioactive Crude Eextracts from chinese medicinal formula Chuanbeipipa dropping pills
title_full_unstemmed Rapid and global identification of potentially bioactive Crude Eextracts from chinese medicinal formula Chuanbeipipa dropping pills
title_sort rapid and global identification of potentially bioactive crude eextracts from chinese medicinal formula chuanbeipipa dropping pills
publishDate 2012
url http://sedici.unlp.edu.ar/handle/10915/8423
http://www.latamjpharm.org/resumenes/31/1/LAJOP_31_1_1_3.pdf
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