Preparation, characterization and in vitro evaluation of stable mucoadhesive intranasal microsphere of L-Dopa

Novel stable mucoadhesive chitosan microspheres were developed to explore the possibility of nasal delivery of L-dopa to avoid first pass metabolism and to improve therapeutic efficiency in treating the symptoms of parkinsonism. The mucoadhesive microspheres were prepared by spray drying using 23 fu...

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Autores principales: Ghodke, Dhananjay S., Naikwade, Nilofar S.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2011
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8315
http://www.latamjpharm.org/resumenes/30/7/LAJOP_30_7_1_26.pdf
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