Anticataleptic activity of various extracts of the aerial parts of Achyranthes aspera

Achyranthes aspera is traditionally used in the treatment of cough and bronchitis and therefore it was our objective to study the effect various extracts of the plant on clonidine and haloperidol induced catalepsy to study its antihistaminic effect. Petroleum ether extract (200 mg/kg, i.p.) of the p...

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Detalles Bibliográficos
Autores principales: Datir, Sandip B., Nirmal, Sunil A., Ganjare, Anjali B., Patil, Manohar J., Dighe, Nachiket S., Mandal, Subhash C.
Formato: Articulo Comunicacion
Lenguaje:Inglés
Publicado: 2011
Materias:
Farmacia
Achyranthes aspera; anticataleptic activity; antiasthmatic; clonidine; haloperidol; β-sitosterol
Extractos Vegetales
Cromatografía
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8216
http://www.latamjpharm.org/resumenes/30/4/LAJOP_30_4_2_3.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-8216
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
Achyranthes aspera; anticataleptic activity; antiasthmatic; clonidine; haloperidol; β-sitosterol
Extractos Vegetales
Cromatografía
spellingShingle Farmacia
Achyranthes aspera; anticataleptic activity; antiasthmatic; clonidine; haloperidol; β-sitosterol
Extractos Vegetales
Cromatografía
Datir, Sandip B.
Nirmal, Sunil A.
Ganjare, Anjali B.
Patil, Manohar J.
Dighe, Nachiket S.
Mandal, Subhash C.
Anticataleptic activity of various extracts of the aerial parts of Achyranthes aspera
topic_facet Farmacia
Achyranthes aspera; anticataleptic activity; antiasthmatic; clonidine; haloperidol; β-sitosterol
Extractos Vegetales
Cromatografía
description Achyranthes aspera is traditionally used in the treatment of cough and bronchitis and therefore it was our objective to study the effect various extracts of the plant on clonidine and haloperidol induced catalepsy to study its antihistaminic effect. Petroleum ether extract (200 mg/kg, i.p.) of the plant significantly inhibited clonidine-induced catalepsy but not inhibited haloperidol-induced catalepsy. This proves the antihistaminic activity of the plant. The extract was standardized by HPTLC in presence of standard β-sitosterol, which proves that the antihistaminic activity may be due to β-sitosterol.
format Articulo
Comunicacion
author Datir, Sandip B.
Nirmal, Sunil A.
Ganjare, Anjali B.
Patil, Manohar J.
Dighe, Nachiket S.
Mandal, Subhash C.
author_facet Datir, Sandip B.
Nirmal, Sunil A.
Ganjare, Anjali B.
Patil, Manohar J.
Dighe, Nachiket S.
Mandal, Subhash C.
author_sort Datir, Sandip B.
title Anticataleptic activity of various extracts of the aerial parts of Achyranthes aspera
title_short Anticataleptic activity of various extracts of the aerial parts of Achyranthes aspera
title_full Anticataleptic activity of various extracts of the aerial parts of Achyranthes aspera
title_fullStr Anticataleptic activity of various extracts of the aerial parts of Achyranthes aspera
title_full_unstemmed Anticataleptic activity of various extracts of the aerial parts of Achyranthes aspera
title_sort anticataleptic activity of various extracts of the aerial parts of achyranthes aspera
publishDate 2011
url http://sedici.unlp.edu.ar/handle/10915/8216
http://www.latamjpharm.org/resumenes/30/4/LAJOP_30_4_2_3.pdf
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