Docking Applied to the Study of Inhibitors of c-Met Kinase
Quinoxaline derivatives were studied as inhibitors of c-Met kinase, a receptor associated with high tumor grade and poor prognosis in a number of human cancers. In this paper we used docking methodologies to predict the binding conformation of a set of quinoxalines and to explain the differences of...
Guardado en:
Autores principales: | , , |
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Formato: | Articulo |
Lenguaje: | Inglés |
Publicado: |
2012
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Materias: | |
Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/81055 |
Aporte de: |
id |
I19-R120-10915-81055 |
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record_format |
dspace |
institution |
Universidad Nacional de La Plata |
institution_str |
I-19 |
repository_str |
R-120 |
collection |
SEDICI (UNLP) |
language |
Inglés |
topic |
Química Quinoxaline c-Met kinase inhibitors |
spellingShingle |
Química Quinoxaline c-Met kinase inhibitors Gavernet, Luciana Palestro, Pablo Hernán Bruno Blanch, Luis Enrique Docking Applied to the Study of Inhibitors of c-Met Kinase |
topic_facet |
Química Quinoxaline c-Met kinase inhibitors |
description |
Quinoxaline derivatives were studied as inhibitors of c-Met kinase, a receptor associated with high tumor grade and poor prognosis in a number of human cancers. In this paper we used docking methodologies to predict the binding conformation of a set of quinoxalines and to explain the differences of biological activities previously reported. |
format |
Articulo Articulo |
author |
Gavernet, Luciana Palestro, Pablo Hernán Bruno Blanch, Luis Enrique |
author_facet |
Gavernet, Luciana Palestro, Pablo Hernán Bruno Blanch, Luis Enrique |
author_sort |
Gavernet, Luciana |
title |
Docking Applied to the Study of Inhibitors of c-Met Kinase |
title_short |
Docking Applied to the Study of Inhibitors of c-Met Kinase |
title_full |
Docking Applied to the Study of Inhibitors of c-Met Kinase |
title_fullStr |
Docking Applied to the Study of Inhibitors of c-Met Kinase |
title_full_unstemmed |
Docking Applied to the Study of Inhibitors of c-Met Kinase |
title_sort |
docking applied to the study of inhibitors of c-met kinase |
publishDate |
2012 |
url |
http://sedici.unlp.edu.ar/handle/10915/81055 |
work_keys_str_mv |
AT gavernetluciana dockingappliedtothestudyofinhibitorsofcmetkinase AT palestropablohernan dockingappliedtothestudyofinhibitorsofcmetkinase AT brunoblanchluisenrique dockingappliedtothestudyofinhibitorsofcmetkinase |
bdutipo_str |
Repositorios |
_version_ |
1764820488062763009 |