Antifungal activity of propolis against Fonsecaea pedrosoi, a chromoblastomycosis agent
Chromoblastomycosis is a subcutaneous mycosis caused by dematiaceous fungi, being Fonsecaea pedrosoi the main etiologic agent in Brazil. Propolis is a resinous material collected by honeybees, with variable composition and pharmacological properties, including antifungal activity. The antifungal act...
Autores principales: | , , , , , , |
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Formato: | Articulo |
Lenguaje: | Inglés |
Publicado: |
2011
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Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/8102 http://www.latamjpharm.org/resumenes/30/1/LAJOP_30_1_1_10.pdf |
Aporte de: |
id |
I19-R120-10915-8102 |
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record_format |
dspace |
institution |
Universidad Nacional de La Plata |
institution_str |
I-19 |
repository_str |
R-120 |
collection |
SEDICI (UNLP) |
language |
Inglés |
topic |
Farmacia actividad antifúngica; cromoblastomicosis; Fonsecaea pedrosoi; compuestos fenólicos; propóleos Hongos Dermatomicosis Compuestos Fenólicos antifungal activity; chromoblastomycosis; Fonsecaea pedrosoi; phenolic compounds; propolis atividade antifúngica; cromoblastomicose; Fonsecaea pedrosoi; compostos fenólicos; própolis |
spellingShingle |
Farmacia actividad antifúngica; cromoblastomicosis; Fonsecaea pedrosoi; compuestos fenólicos; propóleos Hongos Dermatomicosis Compuestos Fenólicos antifungal activity; chromoblastomycosis; Fonsecaea pedrosoi; phenolic compounds; propolis atividade antifúngica; cromoblastomicose; Fonsecaea pedrosoi; compostos fenólicos; própolis Daboit, Tatiane C. Santos, Claisson J. dos Salles, Luisa de A. Heidrich, Daiane Stopiglia, Cheila D.O. Poser, Gilsane Lino von Scroferneker, Maria L. Antifungal activity of propolis against Fonsecaea pedrosoi, a chromoblastomycosis agent |
topic_facet |
Farmacia actividad antifúngica; cromoblastomicosis; Fonsecaea pedrosoi; compuestos fenólicos; propóleos Hongos Dermatomicosis Compuestos Fenólicos antifungal activity; chromoblastomycosis; Fonsecaea pedrosoi; phenolic compounds; propolis atividade antifúngica; cromoblastomicose; Fonsecaea pedrosoi; compostos fenólicos; própolis |
description |
Chromoblastomycosis is a subcutaneous mycosis caused by dematiaceous fungi, being Fonsecaea pedrosoi the main etiologic agent in Brazil. Propolis is a resinous material collected by honeybees, with variable composition and pharmacological properties, including antifungal activity. The antifungal activity of ethanolic extracts of propolis (EEP) obtained from different municipalities of the state of Rio Grande do Sul, Brazil, against F. pedrosoi strains was assessed. The EEP showed MIC values between 625 and 2500 µg/mL and the best antifungal activity were obtained with the propolis collected in Santo Antônio da Patrulha and Candelária. All extracts showed the presence terpenoids with similar chromatographic behavior while flavonoids were abundant in the most active samples. The quantification of phenolic compounds demonstrated that there is no correlation between their concentration and antifungal activity. Thus, it can be concluded that the activity is linked to a qualitative chemical composition and not to the general amount of phenolic compounds |
format |
Articulo Articulo |
author |
Daboit, Tatiane C. Santos, Claisson J. dos Salles, Luisa de A. Heidrich, Daiane Stopiglia, Cheila D.O. Poser, Gilsane Lino von Scroferneker, Maria L. |
author_facet |
Daboit, Tatiane C. Santos, Claisson J. dos Salles, Luisa de A. Heidrich, Daiane Stopiglia, Cheila D.O. Poser, Gilsane Lino von Scroferneker, Maria L. |
author_sort |
Daboit, Tatiane C. |
title |
Antifungal activity of propolis against Fonsecaea pedrosoi, a chromoblastomycosis agent |
title_short |
Antifungal activity of propolis against Fonsecaea pedrosoi, a chromoblastomycosis agent |
title_full |
Antifungal activity of propolis against Fonsecaea pedrosoi, a chromoblastomycosis agent |
title_fullStr |
Antifungal activity of propolis against Fonsecaea pedrosoi, a chromoblastomycosis agent |
title_full_unstemmed |
Antifungal activity of propolis against Fonsecaea pedrosoi, a chromoblastomycosis agent |
title_sort |
antifungal activity of propolis against fonsecaea pedrosoi, a chromoblastomycosis agent |
publishDate |
2011 |
url |
http://sedici.unlp.edu.ar/handle/10915/8102 http://www.latamjpharm.org/resumenes/30/1/LAJOP_30_1_1_10.pdf |
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bdutipo_str |
Repositorios |
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1764820488030257152 |