Antifungal activity of propolis against Fonsecaea pedrosoi, a chromoblastomycosis agent

Chromoblastomycosis is a subcutaneous mycosis caused by dematiaceous fungi, being Fonsecaea pedrosoi the main etiologic agent in Brazil. Propolis is a resinous material collected by honeybees, with variable composition and pharmacological properties, including antifungal activity. The antifungal act...

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Detalles Bibliográficos
Autores principales: Daboit, Tatiane C., Santos, Claisson J. dos, Salles, Luisa de A., Heidrich, Daiane, Stopiglia, Cheila D.O., Poser, Gilsane Lino von, Scroferneker, Maria L.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2011
Materias:
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8102
http://www.latamjpharm.org/resumenes/30/1/LAJOP_30_1_1_10.pdf
Aporte de:
id I19-R120-10915-8102
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
actividad antifúngica; cromoblastomicosis; Fonsecaea pedrosoi; compuestos fenólicos; propóleos
Hongos
Dermatomicosis
Compuestos Fenólicos
antifungal activity; chromoblastomycosis; Fonsecaea pedrosoi; phenolic compounds; propolis
atividade antifúngica; cromoblastomicose; Fonsecaea pedrosoi; compostos fenólicos; própolis
spellingShingle Farmacia
actividad antifúngica; cromoblastomicosis; Fonsecaea pedrosoi; compuestos fenólicos; propóleos
Hongos
Dermatomicosis
Compuestos Fenólicos
antifungal activity; chromoblastomycosis; Fonsecaea pedrosoi; phenolic compounds; propolis
atividade antifúngica; cromoblastomicose; Fonsecaea pedrosoi; compostos fenólicos; própolis
Daboit, Tatiane C.
Santos, Claisson J. dos
Salles, Luisa de A.
Heidrich, Daiane
Stopiglia, Cheila D.O.
Poser, Gilsane Lino von
Scroferneker, Maria L.
Antifungal activity of propolis against Fonsecaea pedrosoi, a chromoblastomycosis agent
topic_facet Farmacia
actividad antifúngica; cromoblastomicosis; Fonsecaea pedrosoi; compuestos fenólicos; propóleos
Hongos
Dermatomicosis
Compuestos Fenólicos
antifungal activity; chromoblastomycosis; Fonsecaea pedrosoi; phenolic compounds; propolis
atividade antifúngica; cromoblastomicose; Fonsecaea pedrosoi; compostos fenólicos; própolis
description Chromoblastomycosis is a subcutaneous mycosis caused by dematiaceous fungi, being Fonsecaea pedrosoi the main etiologic agent in Brazil. Propolis is a resinous material collected by honeybees, with variable composition and pharmacological properties, including antifungal activity. The antifungal activity of ethanolic extracts of propolis (EEP) obtained from different municipalities of the state of Rio Grande do Sul, Brazil, against F. pedrosoi strains was assessed. The EEP showed MIC values between 625 and 2500 µg/mL and the best antifungal activity were obtained with the propolis collected in Santo Antônio da Patrulha and Candelária. All extracts showed the presence terpenoids with similar chromatographic behavior while flavonoids were abundant in the most active samples. The quantification of phenolic compounds demonstrated that there is no correlation between their concentration and antifungal activity. Thus, it can be concluded that the activity is linked to a qualitative chemical composition and not to the general amount of phenolic compounds
format Articulo
Articulo
author Daboit, Tatiane C.
Santos, Claisson J. dos
Salles, Luisa de A.
Heidrich, Daiane
Stopiglia, Cheila D.O.
Poser, Gilsane Lino von
Scroferneker, Maria L.
author_facet Daboit, Tatiane C.
Santos, Claisson J. dos
Salles, Luisa de A.
Heidrich, Daiane
Stopiglia, Cheila D.O.
Poser, Gilsane Lino von
Scroferneker, Maria L.
author_sort Daboit, Tatiane C.
title Antifungal activity of propolis against Fonsecaea pedrosoi, a chromoblastomycosis agent
title_short Antifungal activity of propolis against Fonsecaea pedrosoi, a chromoblastomycosis agent
title_full Antifungal activity of propolis against Fonsecaea pedrosoi, a chromoblastomycosis agent
title_fullStr Antifungal activity of propolis against Fonsecaea pedrosoi, a chromoblastomycosis agent
title_full_unstemmed Antifungal activity of propolis against Fonsecaea pedrosoi, a chromoblastomycosis agent
title_sort antifungal activity of propolis against fonsecaea pedrosoi, a chromoblastomycosis agent
publishDate 2011
url http://sedici.unlp.edu.ar/handle/10915/8102
http://www.latamjpharm.org/resumenes/30/1/LAJOP_30_1_1_10.pdf
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