Extended hildebrand solubility approach in the solubility estimation of the sunscreen ethylhexyl triazone in ethyl acetate + ethanol mixtures

Ethylhexyl triazone (EHT) is a sunscreen agent widely used in the formulation of skin care products, whose physicochemical properties have not been thoroughly studied. In this work the Extended Hildebrand Solubility Approach (EHSA) was applied to evaluate the solubility of EHT in ethyl acetate +...

Descripción completa

Detalles Bibliográficos
Autores principales: Rodríguez, Sylvia J., Cristancho, Diana M., Neita, Paula C., Vargas, Edgar F., Martínez, Fleming
Formato: Articulo
Lenguaje:Inglés
Publicado: 2010
Materias:
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8036
http://www.latamjpharm.org/resumenes/29/7/LAJOP_29_7_1_9.pdf
Aporte de:
id I19-R120-10915-8036
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
ethylhexyl triazone; binary mixtures; extended hildebrand solubility approach; solubility estimation
spellingShingle Farmacia
ethylhexyl triazone; binary mixtures; extended hildebrand solubility approach; solubility estimation
Rodríguez, Sylvia J.
Cristancho, Diana M.
Neita, Paula C.
Vargas, Edgar F.
Martínez, Fleming
Extended hildebrand solubility approach in the solubility estimation of the sunscreen ethylhexyl triazone in ethyl acetate + ethanol mixtures
topic_facet Farmacia
ethylhexyl triazone; binary mixtures; extended hildebrand solubility approach; solubility estimation
description Ethylhexyl triazone (EHT) is a sunscreen agent widely used in the formulation of skin care products, whose physicochemical properties have not been thoroughly studied. In this work the Extended Hildebrand Solubility Approach (EHSA) was applied to evaluate the solubility of EHT in ethyl acetate + ethanol mixtures at 298.15 K. A good correlative capacity of EHSA was found using a regular polynomial model in order five (overall deviation lower than 1.2 %), when the W interaction parameter is related to the solubility parameter of the mixtures. Besides, the deviations obtained in the estimated solubility with respect to experimental solubility were lower compared with those obtained directly by means of an empiric regression of the experimental solubility as a function of the mixtures' solubility parameters.
format Articulo
Articulo
author Rodríguez, Sylvia J.
Cristancho, Diana M.
Neita, Paula C.
Vargas, Edgar F.
Martínez, Fleming
author_facet Rodríguez, Sylvia J.
Cristancho, Diana M.
Neita, Paula C.
Vargas, Edgar F.
Martínez, Fleming
author_sort Rodríguez, Sylvia J.
title Extended hildebrand solubility approach in the solubility estimation of the sunscreen ethylhexyl triazone in ethyl acetate + ethanol mixtures
title_short Extended hildebrand solubility approach in the solubility estimation of the sunscreen ethylhexyl triazone in ethyl acetate + ethanol mixtures
title_full Extended hildebrand solubility approach in the solubility estimation of the sunscreen ethylhexyl triazone in ethyl acetate + ethanol mixtures
title_fullStr Extended hildebrand solubility approach in the solubility estimation of the sunscreen ethylhexyl triazone in ethyl acetate + ethanol mixtures
title_full_unstemmed Extended hildebrand solubility approach in the solubility estimation of the sunscreen ethylhexyl triazone in ethyl acetate + ethanol mixtures
title_sort extended hildebrand solubility approach in the solubility estimation of the sunscreen ethylhexyl triazone in ethyl acetate + ethanol mixtures
publishDate 2010
url http://sedici.unlp.edu.ar/handle/10915/8036
http://www.latamjpharm.org/resumenes/29/7/LAJOP_29_7_1_9.pdf
work_keys_str_mv AT rodriguezsylviaj extendedhildebrandsolubilityapproachinthesolubilityestimationofthesunscreenethylhexyltriazoneinethylacetateethanolmixtures
AT cristanchodianam extendedhildebrandsolubilityapproachinthesolubilityestimationofthesunscreenethylhexyltriazoneinethylacetateethanolmixtures
AT neitapaulac extendedhildebrandsolubilityapproachinthesolubilityestimationofthesunscreenethylhexyltriazoneinethylacetateethanolmixtures
AT vargasedgarf extendedhildebrandsolubilityapproachinthesolubilityestimationofthesunscreenethylhexyltriazoneinethylacetateethanolmixtures
AT martinezfleming extendedhildebrandsolubilityapproachinthesolubilityestimationofthesunscreenethylhexyltriazoneinethylacetateethanolmixtures
bdutipo_str Repositorios
_version_ 1764820486885212163