Enhancement of antibiotic activity by Cordia verbenacea DC

Escherichia coli is known to produce enterotoxins whose properties and its role in diarrheal disease has been extensively investigated. Some species of Staphylococcus are often recognized as etiological agents of many animal and human opportunistic infections. This study is the first test of change...

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Detalles Bibliográficos
Autores principales: Matias, Edinardo F.F., Santos, Karla K. A., Almeida, Thiago S., Costa, José G.M. da, Coutinho, Henrique D.M.
Formato: Articulo Comunicacion
Lenguaje:Inglés
Publicado: 2010
Materias:
Farmacia
Farmacología
antibacterial activity; antibiotics; cordia verbenacea DC.; escherichia coli; hexane extract; methanol extract; modification of resistance; staphylococcus aureus
Extractos de plantas
Bacterias
Agentes antibacterianos
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8026
http://www.latamjpharm.org/resumenes/29/6/LAJOP_29_6_2_11.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-8026
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
Farmacología
antibacterial activity; antibiotics; cordia verbenacea DC.; escherichia coli; hexane extract; methanol extract; modification of resistance; staphylococcus aureus
Extractos de plantas
Bacterias
Agentes antibacterianos
spellingShingle Farmacia
Farmacología
antibacterial activity; antibiotics; cordia verbenacea DC.; escherichia coli; hexane extract; methanol extract; modification of resistance; staphylococcus aureus
Extractos de plantas
Bacterias
Agentes antibacterianos
Matias, Edinardo F.F.
Santos, Karla K. A.
Almeida, Thiago S.
Costa, José G.M. da
Coutinho, Henrique D.M.
Enhancement of antibiotic activity by Cordia verbenacea DC
topic_facet Farmacia
Farmacología
antibacterial activity; antibiotics; cordia verbenacea DC.; escherichia coli; hexane extract; methanol extract; modification of resistance; staphylococcus aureus
Extractos de plantas
Bacterias
Agentes antibacterianos
description Escherichia coli is known to produce enterotoxins whose properties and its role in diarrheal disease has been extensively investigated. Some species of Staphylococcus are often recognized as etiological agents of many animal and human opportunistic infections. This study is the first test of change in resistance of antibiotic activity by Cordia verbenacea DC. against multiresistant strains of Escherichia coli and Staphylococcus aureus. In this study, the hexane and methanol extract of Cordia verbenacea DC. were tested for antibacterial activity alone and in combination with aminoglycosides against bacterial strains. The synergy of the methanolic and hexane were verified by microdilution method. A synergistic effect of both extracts combined with the aminoglycosides was demonstrated. It is therefore suggested that the extracts from Cordia verbenacea DC. could be used as a source of natural products derived from this plant with resistance-modifying antibacterial activity, providing a new weapon against the problem of bacterial resistance to antibiotics.
format Articulo
Comunicacion
author Matias, Edinardo F.F.
Santos, Karla K. A.
Almeida, Thiago S.
Costa, José G.M. da
Coutinho, Henrique D.M.
author_facet Matias, Edinardo F.F.
Santos, Karla K. A.
Almeida, Thiago S.
Costa, José G.M. da
Coutinho, Henrique D.M.
author_sort Matias, Edinardo F.F.
title Enhancement of antibiotic activity by Cordia verbenacea DC
title_short Enhancement of antibiotic activity by Cordia verbenacea DC
title_full Enhancement of antibiotic activity by Cordia verbenacea DC
title_fullStr Enhancement of antibiotic activity by Cordia verbenacea DC
title_full_unstemmed Enhancement of antibiotic activity by Cordia verbenacea DC
title_sort enhancement of antibiotic activity by cordia verbenacea dc
publishDate 2010
url http://sedici.unlp.edu.ar/handle/10915/8026
http://www.latamjpharm.org/resumenes/29/6/LAJOP_29_6_2_11.pdf
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