Phytochemical investigation and anti-Inflammatory activity of Coccinia indica wight and arn. (Cucurbitaceae) fruits

The present work was to study the anti-inflammatory activity of Coccinia indica Wight and Arn fruits belonging to family Cucurbitaceae. The fruit powder of C. indica was subjected to successive extraction with petroleum ether, chloroform, ethanol and water in a Soxhlet extractor. The ethanol extract...

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Detalles Bibliográficos
Autores principales:	Bambal, Vaishali C., Wani, Nitin S., Chaudhari, Sandip P., Deshmukh, Tushar A., Patil, Vijay R.
Formato:	Articulo Comunicacion
Lenguaje:	Inglés
Publicado:	2010
Materias:	Farmacia anti-inflammatory activity; Coccinia indica; indomethacin Medicamentos Farmacología Plantas medicinales Agentes antiinflamatorios
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/7990 http://www.latamjpharm.org/resumenes/29/5/LAJOP_29_5_2_8.pdf
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

id	I19-R120-10915-7990
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institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Farmacia anti-inflammatory activity; Coccinia indica; indomethacin Medicamentos Farmacología Plantas medicinales Agentes antiinflamatorios
spellingShingle	Farmacia anti-inflammatory activity; Coccinia indica; indomethacin Medicamentos Farmacología Plantas medicinales Agentes antiinflamatorios Bambal, Vaishali C. Wani, Nitin S. Chaudhari, Sandip P. Deshmukh, Tushar A. Patil, Vijay R. Phytochemical investigation and anti-Inflammatory activity of Coccinia indica wight and arn. (Cucurbitaceae) fruits
topic_facet	Farmacia anti-inflammatory activity; Coccinia indica; indomethacin Medicamentos Farmacología Plantas medicinales Agentes antiinflamatorios
description	The present work was to study the anti-inflammatory activity of Coccinia indica Wight and Arn fruits belonging to family Cucurbitaceae. The fruit powder of C. indica was subjected to successive extraction with petroleum ether, chloroform, ethanol and water in a Soxhlet extractor. The ethanol extract after preliminary phytochemical investigation shown the presence of glycosides, triterpenoids, flavonoids, tannins and phenolic compounds. The anti-inflammatory activity was studied using carrageenan-induced rat paw oedema and cotton pellet granuloma at three different doses (100, 200 and 400 mg/kg b.w. p.o.) of each extract. The ethanol extract of C. indica fruits exhibited significant anti-inflammatory activity at the dose of 200 mg/kg and 400 mg/kg in both models when compared with control group. Indomethacin (10 mg/kg b.w. p.o) also showed significant anti-inflammatory activity in both models.
format	Articulo Comunicacion
author	Bambal, Vaishali C. Wani, Nitin S. Chaudhari, Sandip P. Deshmukh, Tushar A. Patil, Vijay R.
author_facet	Bambal, Vaishali C. Wani, Nitin S. Chaudhari, Sandip P. Deshmukh, Tushar A. Patil, Vijay R.
author_sort	Bambal, Vaishali C.
title	Phytochemical investigation and anti-Inflammatory activity of Coccinia indica wight and arn. (Cucurbitaceae) fruits
title_short	Phytochemical investigation and anti-Inflammatory activity of Coccinia indica wight and arn. (Cucurbitaceae) fruits
title_full	Phytochemical investigation and anti-Inflammatory activity of Coccinia indica wight and arn. (Cucurbitaceae) fruits
title_fullStr	Phytochemical investigation and anti-Inflammatory activity of Coccinia indica wight and arn. (Cucurbitaceae) fruits
title_full_unstemmed	Phytochemical investigation and anti-Inflammatory activity of Coccinia indica wight and arn. (Cucurbitaceae) fruits
title_sort	phytochemical investigation and anti-inflammatory activity of coccinia indica wight and arn. (cucurbitaceae) fruits
publishDate	2010
url	http://sedici.unlp.edu.ar/handle/10915/7990 http://www.latamjpharm.org/resumenes/29/5/LAJOP_29_5_2_8.pdf
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Phytochemical investigation and anti-Inflammatory activity of Coccinia indica wight and arn. (Cucurbitaceae) fruits

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