A new antibacterial pyridinoside from a Streptomyces species
A new compound, 8-propionate-2-β-(D+)-glucosyl-9,10-pyranopyridine, was isolated from the chloroform extract of a Streptomyces species. The structure of the compound was confirmed by spectroscopic techniques including UV, IR, HR-ESI-MS, 1H-NMR, 13C-NMR, 1H-1H COSY and HMBC (long range coupling) spec...
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Autores principales: | , , , |
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Formato: | Articulo |
Lenguaje: | Inglés |
Publicado: |
2010
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Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/7949 http://www.latamjpharm.org/resumenes/29/4/LAJOP_29_4_1_12.pdf |
Aporte de: |
id |
I19-R120-10915-7949 |
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record_format |
dspace |
institution |
Universidad Nacional de La Plata |
institution_str |
I-19 |
repository_str |
R-120 |
collection |
SEDICI (UNLP) |
language |
Inglés |
topic |
Farmacia antibacterial activity; 8-propionate-2-β-(D+)-glucosyl-9;10-pyranopyridine; Streptomyces species Farmacología Bacterias Bacterias gram-positivas |
spellingShingle |
Farmacia antibacterial activity; 8-propionate-2-β-(D+)-glucosyl-9;10-pyranopyridine; Streptomyces species Farmacología Bacterias Bacterias gram-positivas Barman, Ranjan K. Gafur, Mohammad A. Rahman, Bytul M. Khondkar, Proma A new antibacterial pyridinoside from a Streptomyces species |
topic_facet |
Farmacia antibacterial activity; 8-propionate-2-β-(D+)-glucosyl-9;10-pyranopyridine; Streptomyces species Farmacología Bacterias Bacterias gram-positivas |
description |
A new compound, 8-propionate-2-β-(D+)-glucosyl-9,10-pyranopyridine, was isolated from the chloroform extract of a Streptomyces species. The structure of the compound was confirmed by spectroscopic techniques including UV, IR, HR-ESI-MS, 1H-NMR, 13C-NMR, 1H-1H COSY and HMBC (long range coupling) spectra. The compound showed significant antibacterial activity against Gram-positive bacteria. The minimum inhibitory concentrations (MIC) of the isolated compound against Bacillus megaterium, Streptococcus β-haemolyticus, Bacillus subtilis, Escherichia coli, Salmonella typhi and Shigella dysenteriae were found to be 0.16, 0.08, 0.08, 0.04, 0.08 and 0.08 μM, respectively. |
format |
Articulo Articulo |
author |
Barman, Ranjan K. Gafur, Mohammad A. Rahman, Bytul M. Khondkar, Proma |
author_facet |
Barman, Ranjan K. Gafur, Mohammad A. Rahman, Bytul M. Khondkar, Proma |
author_sort |
Barman, Ranjan K. |
title |
A new antibacterial pyridinoside from a Streptomyces species |
title_short |
A new antibacterial pyridinoside from a Streptomyces species |
title_full |
A new antibacterial pyridinoside from a Streptomyces species |
title_fullStr |
A new antibacterial pyridinoside from a Streptomyces species |
title_full_unstemmed |
A new antibacterial pyridinoside from a Streptomyces species |
title_sort |
new antibacterial pyridinoside from a streptomyces species |
publishDate |
2010 |
url |
http://sedici.unlp.edu.ar/handle/10915/7949 http://www.latamjpharm.org/resumenes/29/4/LAJOP_29_4_1_12.pdf |
work_keys_str_mv |
AT barmanranjank anewantibacterialpyridinosidefromastreptomycesspecies AT gafurmohammada anewantibacterialpyridinosidefromastreptomycesspecies AT rahmanbytulm anewantibacterialpyridinosidefromastreptomycesspecies AT khondkarproma anewantibacterialpyridinosidefromastreptomycesspecies AT barmanranjank newantibacterialpyridinosidefromastreptomycesspecies AT gafurmohammada newantibacterialpyridinosidefromastreptomycesspecies AT rahmanbytulm newantibacterialpyridinosidefromastreptomycesspecies AT khondkarproma newantibacterialpyridinosidefromastreptomycesspecies |
bdutipo_str |
Repositorios |
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1764820486812860416 |