Effects of D-003 (sugarcane wax acids) on the physical exercise on static bicycle test

Physical inactivity and low maximal exercise oxygen consumption (VO2max) are predictors of mortality and coronary events in adults, respectively. Lowering serum cholesterol and platelet aggregation benefits cardiovascular function in aging persons. D-003, a mixture of sugarcane wax acids, exhibits...

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Detalles Bibliográficos
Autores principales: Pérez, Pablo, Illnait, José, Fernández, Lilia, Mesa, Meylis, Fernández, Julio, Gámez, Rafael, Más, Rosa, Gómez, Mainel, Ruiz, Dalmer, Jardines, Yunaisi
Formato: Articulo
Lenguaje:Inglés
Publicado: 2010
Materias:
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/7903
http://www.latamjpharm.org/resumenes/29/2/LAJOP_29_2_1_15.pdf
Aporte de:
id I19-R120-10915-7903
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
lipid-lowering effects; physical fitness; static bicycle; sugarcane wax acids; VO2max
Farmacología
Enfermedades cardiovasculares
spellingShingle Farmacia
lipid-lowering effects; physical fitness; static bicycle; sugarcane wax acids; VO2max
Farmacología
Enfermedades cardiovasculares
Pérez, Pablo
Illnait, José
Fernández, Lilia
Mesa, Meylis
Fernández, Julio
Gámez, Rafael
Más, Rosa
Gómez, Mainel
Ruiz, Dalmer
Jardines, Yunaisi
Effects of D-003 (sugarcane wax acids) on the physical exercise on static bicycle test
topic_facet Farmacia
lipid-lowering effects; physical fitness; static bicycle; sugarcane wax acids; VO2max
Farmacología
Enfermedades cardiovasculares
description Physical inactivity and low maximal exercise oxygen consumption (VO2max) are predictors of mortality and coronary events in adults, respectively. Lowering serum cholesterol and platelet aggregation benefits cardiovascular function in aging persons. D-003, a mixture of sugarcane wax acids, exhibits antiplatelet and cholesterol-lowering effects, and could benefit the performance of middle-aged and older subjects in effort tests. This randomised, double-blinded, placebo-controlled study investigated the effects of D-003 (10 mg/day) for 12 weeks on the effort test in the static bicycle and the health status of 50 subjects (50-70 years old). Compared with baseline and placebo, D-003 improved significantly VO2 max values, pain/discomfort and health perception EuroQoL scores, and the cardiovascular capacity assessed by the Specific Activity Scale. Also, D-003 displayed cholesterol-lowering effects versus placebo, being well tolerated. There were no study withdrawals. Concluding, D-003 improved VO2 max values in the effort test, lipid profile, health perception and cardiovascular status of study subjects.
format Articulo
Articulo
author Pérez, Pablo
Illnait, José
Fernández, Lilia
Mesa, Meylis
Fernández, Julio
Gámez, Rafael
Más, Rosa
Gómez, Mainel
Ruiz, Dalmer
Jardines, Yunaisi
author_facet Pérez, Pablo
Illnait, José
Fernández, Lilia
Mesa, Meylis
Fernández, Julio
Gámez, Rafael
Más, Rosa
Gómez, Mainel
Ruiz, Dalmer
Jardines, Yunaisi
author_sort Pérez, Pablo
title Effects of D-003 (sugarcane wax acids) on the physical exercise on static bicycle test
title_short Effects of D-003 (sugarcane wax acids) on the physical exercise on static bicycle test
title_full Effects of D-003 (sugarcane wax acids) on the physical exercise on static bicycle test
title_fullStr Effects of D-003 (sugarcane wax acids) on the physical exercise on static bicycle test
title_full_unstemmed Effects of D-003 (sugarcane wax acids) on the physical exercise on static bicycle test
title_sort effects of d-003 (sugarcane wax acids) on the physical exercise on static bicycle test
publishDate 2010
url http://sedici.unlp.edu.ar/handle/10915/7903
http://www.latamjpharm.org/resumenes/29/2/LAJOP_29_2_1_15.pdf
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