Dietary and Hormonal Factors Involved in Healthy or Unhealthy Visceral Adipose Tissue Expansion

White adipose tissue (WAT) expansion is related to the development of metabolic disorders found in obesity. WAT expansion is the result of generation of new adipose cells by activation of adipogenesis and/or the increase in adipose cell size (hypertrophy). The balance between these two processes det...

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Autores principales: Zubiría, María Guillermina, Alzamendi, Ana, Ongaro Gambino, Luisina, Spinedi, Eduardo Julio, Giovambattista, Andrés, Gordeladze, Jan
Formato: Libro Capitulo de libro
Lenguaje:Inglés
Publicado: Intech 2017
Materias:
Ciencias Exactas
Ciencias Médicas
Adiposidad
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/74721
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-74721
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Exactas
Ciencias Médicas
Adiposidad
spellingShingle Ciencias Exactas
Ciencias Médicas
Adiposidad
Zubiría, María Guillermina
Alzamendi, Ana
Ongaro Gambino, Luisina
Spinedi, Eduardo Julio
Giovambattista, Andrés
Gordeladze, Jan
Dietary and Hormonal Factors Involved in Healthy or Unhealthy Visceral Adipose Tissue Expansion
topic_facet Ciencias Exactas
Ciencias Médicas
Adiposidad
description White adipose tissue (WAT) expansion is related to the development of metabolic disorders found in obesity. WAT expansion is the result of generation of new adipose cells by activation of adipogenesis and/or the increase in adipose cell size (hypertrophy). The balance between these two processes determines whether WAT expansion occurs predominantly by hyperplasia, which means the increase in the number of adipocytes, or hypertrophy. Hypertrophic adipocytes are characterized by changes in adipokine secretion pattern, insulin resistance and altered lipid metabolism, which is the reason why WAT-hypertrophic expansion is considered unhealthy. Conversely, the generation of new mature adipocytes by adipogenesis contributes to reduction of the development of hypertrophic adipocytes and therefore maintain normal WAT functions, leading to healthy hyperplastic expansion. The adipogenic capacity of adipose tissue depends on the adipogenic potential and the number of adipocyte precursor cells. Different factors are known to regulate adipogenic process and adipose tissue function, contributing to a healthy or unhealthy expansion that occurs under positive energy balance. This chapter discusses the role of fructose intake and glucocorticoids and testosterone as regulators of adipose tissue function and expansion.
format Libro
Capitulo de libro
author Zubiría, María Guillermina
Alzamendi, Ana
Ongaro Gambino, Luisina
Spinedi, Eduardo Julio
Giovambattista, Andrés
Gordeladze, Jan
author_facet Zubiría, María Guillermina
Alzamendi, Ana
Ongaro Gambino, Luisina
Spinedi, Eduardo Julio
Giovambattista, Andrés
Gordeladze, Jan
author_sort Zubiría, María Guillermina
title Dietary and Hormonal Factors Involved in Healthy or Unhealthy Visceral Adipose Tissue Expansion
title_short Dietary and Hormonal Factors Involved in Healthy or Unhealthy Visceral Adipose Tissue Expansion
title_full Dietary and Hormonal Factors Involved in Healthy or Unhealthy Visceral Adipose Tissue Expansion
title_fullStr Dietary and Hormonal Factors Involved in Healthy or Unhealthy Visceral Adipose Tissue Expansion
title_full_unstemmed Dietary and Hormonal Factors Involved in Healthy or Unhealthy Visceral Adipose Tissue Expansion
title_sort dietary and hormonal factors involved in healthy or unhealthy visceral adipose tissue expansion
publisher Intech
publishDate 2017
url http://sedici.unlp.edu.ar/handle/10915/74721
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