Optimal experimental design for process optimization with stochastic binary outcomes

Effective control of the end-use properties in order to guarantee product quality is of paramount importance. This is especially valuable for products such as medicament, polymers and nanomaterials. There are plenty of innovative processes whose principles of operation are unknown and for which is n...

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Detalles Bibliográficos
Autores principales: Colombo, Estefanía, Luna, Martín, Martínez, Ernesto
Formato: Objeto de conferencia
Lenguaje:Inglés
Publicado: 2015
Materias:
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/58819
http://44jaiio.sadio.org.ar/sites/default/files/sii1-12.pdf
Aporte de:
id I19-R120-10915-58819
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Informáticas
Optimization
optimal experimental design
end-use properties
spellingShingle Ciencias Informáticas
Optimization
optimal experimental design
end-use properties
Colombo, Estefanía
Luna, Martín
Martínez, Ernesto
Optimal experimental design for process optimization with stochastic binary outcomes
topic_facet Ciencias Informáticas
Optimization
optimal experimental design
end-use properties
description Effective control of the end-use properties in order to guarantee product quality is of paramount importance. This is especially valuable for products such as medicament, polymers and nanomaterials. There are plenty of innovative processes whose principles of operation are unknown and for which is not possible to develop reliable models due to time and cost. Despite this, it is important to know the optimum operating zone where the process should work to ensure that the end product meets the required properties. To address this issue, a run-to-run optimization approach is proposed to find the reduced region of operation which guarantees obtaining end-use properties with high probability when a first-principles model for the batch process is not available a priori. In order to evaluate the effectiveness of the methodology to find optimal policies for runs involving stochastic binary outcomes, the well-known example of the emulsion polymerization of styrene has been addressed. Results obtained demonstrated that the proposed method is a powerful tool for optimal design of experiments aiming to guarantee end-use product properties.
format Objeto de conferencia
Objeto de conferencia
author Colombo, Estefanía
Luna, Martín
Martínez, Ernesto
author_facet Colombo, Estefanía
Luna, Martín
Martínez, Ernesto
author_sort Colombo, Estefanía
title Optimal experimental design for process optimization with stochastic binary outcomes
title_short Optimal experimental design for process optimization with stochastic binary outcomes
title_full Optimal experimental design for process optimization with stochastic binary outcomes
title_fullStr Optimal experimental design for process optimization with stochastic binary outcomes
title_full_unstemmed Optimal experimental design for process optimization with stochastic binary outcomes
title_sort optimal experimental design for process optimization with stochastic binary outcomes
publishDate 2015
url http://sedici.unlp.edu.ar/handle/10915/58819
http://44jaiio.sadio.org.ar/sites/default/files/sii1-12.pdf
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AT lunamartin optimalexperimentaldesignforprocessoptimizationwithstochasticbinaryoutcomes
AT martinezernesto optimalexperimentaldesignforprocessoptimizationwithstochasticbinaryoutcomes
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