Essential oil from eucalyptus benthamii Maiden et Cambage reduces nitric oxide production in lipopolysaccharide-induced murine peritoneal macrophages
Few studies are concerned about the essential oil extracted from leaves of Eucalyptus benthamii Maiden et Cambage that shows high content of α-pinene. The goal of this paper was to investigate the in vitro effect of the essential oil of E. benthamii and α-pinene on lipopolysaccharide (LPS)-induced n...
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Autores principales: | , , , , , |
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Formato: | Articulo |
Lenguaje: | Inglés |
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2012
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Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/20179 http://www.latamjpharm.org/resumenes/31/4/LAJOP_31_4_1_8.pdf |
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id |
I19-R120-10915-20179 |
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institution |
Universidad Nacional de La Plata |
institution_str |
I-19 |
repository_str |
R-120 |
collection |
SEDICI (UNLP) |
language |
Inglés |
topic |
Farmacia aceite esencial Óxido Nítrico Myrtaceae α-pinene essential oil eucalyptus benthamii nitric oxide production |
spellingShingle |
Farmacia aceite esencial Óxido Nítrico Myrtaceae α-pinene essential oil eucalyptus benthamii nitric oxide production Döll-Boscardini, Patrícia M. Almeida, Martinha A. Nakashima, Tomoe Paula, Josiane de F. Padilha de Kanunfre, Carla C. Farago, Paulo V. Essential oil from eucalyptus benthamii Maiden et Cambage reduces nitric oxide production in lipopolysaccharide-induced murine peritoneal macrophages |
topic_facet |
Farmacia aceite esencial Óxido Nítrico Myrtaceae α-pinene essential oil eucalyptus benthamii nitric oxide production |
description |
Few studies are concerned about the essential oil extracted from leaves of Eucalyptus benthamii Maiden et Cambage that shows high content of α-pinene. The goal of this paper was to investigate the in vitro effect of the essential oil of E. benthamii and α-pinene on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in mouse peritoneal macrophages. Macrophages were harvested by washing with phosphate buffered saline and cultured with 10 μg/mL LPS. Three concentrations (5, 10, and 20 μg/mL) of the essential oil of E. benthamii and α-pinene were investigated. Nitrite levels were measured based on the Griess reaction, an indirect assay for NO production. The essential oil of E. benthamii significantly suppressed NO production in murine peritoneal macrophages at 10 and 20 μg/mL. In contrast, α-pinene did not inhibit NO production. |
format |
Articulo Articulo |
author |
Döll-Boscardini, Patrícia M. Almeida, Martinha A. Nakashima, Tomoe Paula, Josiane de F. Padilha de Kanunfre, Carla C. Farago, Paulo V. |
author_facet |
Döll-Boscardini, Patrícia M. Almeida, Martinha A. Nakashima, Tomoe Paula, Josiane de F. Padilha de Kanunfre, Carla C. Farago, Paulo V. |
author_sort |
Döll-Boscardini, Patrícia M. |
title |
Essential oil from eucalyptus benthamii Maiden et Cambage reduces nitric oxide production in lipopolysaccharide-induced murine peritoneal macrophages |
title_short |
Essential oil from eucalyptus benthamii Maiden et Cambage reduces nitric oxide production in lipopolysaccharide-induced murine peritoneal macrophages |
title_full |
Essential oil from eucalyptus benthamii Maiden et Cambage reduces nitric oxide production in lipopolysaccharide-induced murine peritoneal macrophages |
title_fullStr |
Essential oil from eucalyptus benthamii Maiden et Cambage reduces nitric oxide production in lipopolysaccharide-induced murine peritoneal macrophages |
title_full_unstemmed |
Essential oil from eucalyptus benthamii Maiden et Cambage reduces nitric oxide production in lipopolysaccharide-induced murine peritoneal macrophages |
title_sort |
essential oil from eucalyptus benthamii maiden et cambage reduces nitric oxide production in lipopolysaccharide-induced murine peritoneal macrophages |
publishDate |
2012 |
url |
http://sedici.unlp.edu.ar/handle/10915/20179 http://www.latamjpharm.org/resumenes/31/4/LAJOP_31_4_1_8.pdf |
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Repositorios |
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