Free radical scavenging and anti-edematogenic activities of essential oil obtained from trichilia silvatica dc. (meliaceae) leaves

The present study was focused in evaluating the chemical composition, the anti-edematogenic and antioxidant activities of essential oil obtained from Trichilia silvatica (EOTS) leaves. The EOTS was extracted by hydrodistillation and their analyses were performed by GC/MS. The main compounds identifi...

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Detalles Bibliográficos
Autores principales:	Formagio, Anelise Samara Nazari, Santos, Luiz A. C. dos, Cardoso, Claudia A. L., Silva, Magaiver A., Zárate, Nestor A. H., Vieira, Maria do C., Kassuya, Cândida A. L., Caramão, Elina B.
Formato:	Articulo
Lenguaje:	Inglés
Publicado:	2012
Materias:	Farmacia Agentes Antiinflamatorios Análisis Químico antioxidant activity anti-edematogenic activity essential oil trichilia silvatica
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/18274 http://www.latamjpharm.org/resumenes/31/3/LAJOP_31_3_1_18.pdf
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

id	I19-R120-10915-18274
record_format	dspace
institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Farmacia Agentes Antiinflamatorios Análisis Químico antioxidant activity anti-edematogenic activity essential oil trichilia silvatica
spellingShingle	Farmacia Agentes Antiinflamatorios Análisis Químico antioxidant activity anti-edematogenic activity essential oil trichilia silvatica Formagio, Anelise Samara Nazari Santos, Luiz A. C. dos Cardoso, Claudia A. L. Silva, Magaiver A. Zárate, Nestor A. H. Vieira, Maria do C. Kassuya, Cândida A. L. Caramão, Elina B. Free radical scavenging and anti-edematogenic activities of essential oil obtained from trichilia silvatica dc. (meliaceae) leaves
topic_facet	Farmacia Agentes Antiinflamatorios Análisis Químico antioxidant activity anti-edematogenic activity essential oil trichilia silvatica
description	The present study was focused in evaluating the chemical composition, the anti-edematogenic and antioxidant activities of essential oil obtained from Trichilia silvatica (EOTS) leaves. The EOTS was extracted by hydrodistillation and their analyses were performed by GC/MS. The main compounds identified in the EOTS were sesquiterpenes. Furthermore, the EOTS exhibited antioxidant and in vivo anti-inflammatory activity. The oral administration of EOTS (100 and 300 mg/kg), significantly inhibited the carrageenan (Cg) induced rat paw edema. The observed inhibitions were 54 ± 7 and 49 ± 6 % (100 mg/kg) for EOTS and 68 ± 6 % and 66 ± 11 % for dexamethasone after 2 and 4 h after Cg-injection, respectively. In conclusion, the present work showed for the first time, that the anti-inflammatory effects of essential oil seem to be mainly associated with the high levels of sesquiterpene in the leaves of this plant.
format	Articulo Articulo
author	Formagio, Anelise Samara Nazari Santos, Luiz A. C. dos Cardoso, Claudia A. L. Silva, Magaiver A. Zárate, Nestor A. H. Vieira, Maria do C. Kassuya, Cândida A. L. Caramão, Elina B.
author_facet	Formagio, Anelise Samara Nazari Santos, Luiz A. C. dos Cardoso, Claudia A. L. Silva, Magaiver A. Zárate, Nestor A. H. Vieira, Maria do C. Kassuya, Cândida A. L. Caramão, Elina B.
author_sort	Formagio, Anelise Samara Nazari
title	Free radical scavenging and anti-edematogenic activities of essential oil obtained from trichilia silvatica dc. (meliaceae) leaves
title_short	Free radical scavenging and anti-edematogenic activities of essential oil obtained from trichilia silvatica dc. (meliaceae) leaves
title_full	Free radical scavenging and anti-edematogenic activities of essential oil obtained from trichilia silvatica dc. (meliaceae) leaves
title_fullStr	Free radical scavenging and anti-edematogenic activities of essential oil obtained from trichilia silvatica dc. (meliaceae) leaves
title_full_unstemmed	Free radical scavenging and anti-edematogenic activities of essential oil obtained from trichilia silvatica dc. (meliaceae) leaves
title_sort	free radical scavenging and anti-edematogenic activities of essential oil obtained from trichilia silvatica dc. (meliaceae) leaves
publishDate	2012
url	http://sedici.unlp.edu.ar/handle/10915/18274 http://www.latamjpharm.org/resumenes/31/3/LAJOP_31_3_1_18.pdf
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Free radical scavenging and anti-edematogenic activities of essential oil obtained from trichilia silvatica dc. (meliaceae) leaves

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