Production and characterization of a new detergent‑stable keratinase expressed by Pedobacter sp. 3.14.7, a novel Antarctic psychrotolerant keratin‑degrading bacterium

Background: Antarctica is one of the harshest environments in the world. Despite this fact, it has been colonized by microorganisms, which had to develop different adaptations in order to survive. By studying their enzymes, we can harness these adaptations in order to use them in various industrial...

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Autores principales: Rios Cruz, Patricia Leonela, Bezus, Brenda, Cavalitto, Sebastián Fernando, Cavello, Ivana Alejandra
Formato: Articulo
Lenguaje:Inglés
Publicado: 2022
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/154706
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spelling I19-R120-10915-1547062023-06-27T20:07:03Z http://sedici.unlp.edu.ar/handle/10915/154706 issn:2090-5920 Production and characterization of a new detergent‑stable keratinase expressed by Pedobacter sp. 3.14.7, a novel Antarctic psychrotolerant keratin‑degrading bacterium Rios Cruz, Patricia Leonela Bezus, Brenda Cavalitto, Sebastián Fernando Cavello, Ivana Alejandra 2022 2023-06-27T13:05:36Z en Ciencias Exactas Química Cold active keratinase Pedobacter Keratin biodegradation Background: Antarctica is one of the harshest environments in the world. Despite this fact, it has been colonized by microorganisms, which had to develop different adaptations in order to survive. By studying their enzymes, we can harness these adaptations in order to use them in various industrial processes. Keratinases (E.C. 3.4.99.11) are characterized by their robustness in withstanding extreme conditions and, along with other enzymes, are commonly added to laundry detergents, which makes their study of industrial interest. Results: In this work, a novel keratinase producer, Pedobacter sp. 3.14.7 (MF 347939.1), isolated from Antarctic birds’ nests, was identified. This psychrotolerant isolate displays a typical psychrotolerant growth pattern, with an optimal temperature of 20 °C (μmax=0.23 h⁻¹). After 238 h, maximum proteolytic (22.00 ± 1.17 U ml⁻¹) and keratinolytic (33.04 ± 1.09 U ml⁻¹) activities were achieved with a feather sample conversion of approximately 85%. The keratinase present in crude extract was characterized as a metalloprotease with a molecular weight of 25 kDa, stable in a wide range of pH, with an optimum pH of 7.5. Optimum temperature was 55 °C. Wash performance at 20 °C using this crude extract could remove completely blood stain from cotton cloth. Conclusion: We report a new keratinolytic bacteria from maritime Antarctica. Among its biochemical characteristics, its stability in the presence of different detergents and bleaching agents and its wash performance showed promising results regarding its potential use as a laundry detergent additive. Centro de Investigación y Desarrollo en Fermentaciones Industriales Articulo Articulo http://creativecommons.org/licenses/by/4.0/ Creative Commons Attribution 4.0 International (CC BY 4.0) application/pdf
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Exactas
Química
Cold active keratinase
Pedobacter
Keratin biodegradation
spellingShingle Ciencias Exactas
Química
Cold active keratinase
Pedobacter
Keratin biodegradation
Rios Cruz, Patricia Leonela
Bezus, Brenda
Cavalitto, Sebastián Fernando
Cavello, Ivana Alejandra
Production and characterization of a new detergent‑stable keratinase expressed by Pedobacter sp. 3.14.7, a novel Antarctic psychrotolerant keratin‑degrading bacterium
topic_facet Ciencias Exactas
Química
Cold active keratinase
Pedobacter
Keratin biodegradation
description Background: Antarctica is one of the harshest environments in the world. Despite this fact, it has been colonized by microorganisms, which had to develop different adaptations in order to survive. By studying their enzymes, we can harness these adaptations in order to use them in various industrial processes. Keratinases (E.C. 3.4.99.11) are characterized by their robustness in withstanding extreme conditions and, along with other enzymes, are commonly added to laundry detergents, which makes their study of industrial interest. Results: In this work, a novel keratinase producer, Pedobacter sp. 3.14.7 (MF 347939.1), isolated from Antarctic birds’ nests, was identified. This psychrotolerant isolate displays a typical psychrotolerant growth pattern, with an optimal temperature of 20 °C (μmax=0.23 h⁻¹). After 238 h, maximum proteolytic (22.00 ± 1.17 U ml⁻¹) and keratinolytic (33.04 ± 1.09 U ml⁻¹) activities were achieved with a feather sample conversion of approximately 85%. The keratinase present in crude extract was characterized as a metalloprotease with a molecular weight of 25 kDa, stable in a wide range of pH, with an optimum pH of 7.5. Optimum temperature was 55 °C. Wash performance at 20 °C using this crude extract could remove completely blood stain from cotton cloth. Conclusion: We report a new keratinolytic bacteria from maritime Antarctica. Among its biochemical characteristics, its stability in the presence of different detergents and bleaching agents and its wash performance showed promising results regarding its potential use as a laundry detergent additive.
format Articulo
Articulo
author Rios Cruz, Patricia Leonela
Bezus, Brenda
Cavalitto, Sebastián Fernando
Cavello, Ivana Alejandra
author_facet Rios Cruz, Patricia Leonela
Bezus, Brenda
Cavalitto, Sebastián Fernando
Cavello, Ivana Alejandra
author_sort Rios Cruz, Patricia Leonela
title Production and characterization of a new detergent‑stable keratinase expressed by Pedobacter sp. 3.14.7, a novel Antarctic psychrotolerant keratin‑degrading bacterium
title_short Production and characterization of a new detergent‑stable keratinase expressed by Pedobacter sp. 3.14.7, a novel Antarctic psychrotolerant keratin‑degrading bacterium
title_full Production and characterization of a new detergent‑stable keratinase expressed by Pedobacter sp. 3.14.7, a novel Antarctic psychrotolerant keratin‑degrading bacterium
title_fullStr Production and characterization of a new detergent‑stable keratinase expressed by Pedobacter sp. 3.14.7, a novel Antarctic psychrotolerant keratin‑degrading bacterium
title_full_unstemmed Production and characterization of a new detergent‑stable keratinase expressed by Pedobacter sp. 3.14.7, a novel Antarctic psychrotolerant keratin‑degrading bacterium
title_sort production and characterization of a new detergent‑stable keratinase expressed by pedobacter sp. 3.14.7, a novel antarctic psychrotolerant keratin‑degrading bacterium
publishDate 2022
url http://sedici.unlp.edu.ar/handle/10915/154706
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