Enrofloxacin and Ciprofloxacin Residues in Broiler Chicken Feathers after Enrofloxacin Oral Administration

Antibiotics in animal feed are a public health concern. Drug residues could eventually be detected in animal food products intended for human consumption. Our aim was to study the residue depletion of enrofloxacin and its metabolite ciprofloxacin in broiler chicken feathers. A validated HPLC-fluores...

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Autores principales: Marchetti, María Laura, Buchamer, Andrea Verónica, Buldain, Daniel Cornelio, Mestorino, Olga Nora
Formato: Articulo
Lenguaje:Inglés
Publicado: 2019
Materias:
Ciencias Veterinarias
Antimicrobials
Enrofloxacin
Ciprofloxacin
Feathers
Poultry
Residues
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/153595
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-153595
record_format dspace
spelling I19-R120-10915-1535952023-05-30T04:06:32Z http://sedici.unlp.edu.ar/handle/10915/153595 issn:2306-7381 Enrofloxacin and Ciprofloxacin Residues in Broiler Chicken Feathers after Enrofloxacin Oral Administration Marchetti, María Laura Buchamer, Andrea Verónica Buldain, Daniel Cornelio Mestorino, Olga Nora 2019 2023-05-29T18:33:00Z en Ciencias Veterinarias Antimicrobials Enrofloxacin Ciprofloxacin Feathers Poultry Residues Antibiotics in animal feed are a public health concern. Drug residues could eventually be detected in animal food products intended for human consumption. Our aim was to study the residue depletion of enrofloxacin and its metabolite ciprofloxacin in broiler chicken feathers. A validated HPLC-fluorescence method was used to quantify both compounds in feather samples. Broiler chickens were treated through drinking water with 10 mg Kg-1 d of enrofloxacin for 5 consecutive days. Feather samples were taken from 10 random birds per day until 9 days. Extraction was performed by a liquid/liquid technique. Both fluoroquinolones concentrations were determined by liquid chromatography with fluorescence detection. High levels of enrofloxacin and ciprofloxacin were found in feathers after oral administration and these compounds were detected for 9 days. Feather meal is a potential source of drug residues that can pass through the food chain when contaminated meal is fed to food-producing animals. In the present study enrofloxacin and ciprofloxacin concentrations were 0.20 to 5.46 μg g-1 between 1 to 9 days after final treatment, which means that withdrawal time fit for edible tissues is not adequate to reduce antimicrobial residues in chicken feathers. Further studies to establish a withdrawal time may be useful to avoid that drug residues could result in adverse health consequences like increase in antibiotic resistance. Facultad de Ciencias Veterinarias Articulo Articulo http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf 180-186
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Veterinarias
Antimicrobials
Enrofloxacin
Ciprofloxacin
Feathers
Poultry
Residues
spellingShingle Ciencias Veterinarias
Antimicrobials
Enrofloxacin
Ciprofloxacin
Feathers
Poultry
Residues
Marchetti, María Laura
Buchamer, Andrea Verónica
Buldain, Daniel Cornelio
Mestorino, Olga Nora
Enrofloxacin and Ciprofloxacin Residues in Broiler Chicken Feathers after Enrofloxacin Oral Administration
topic_facet Ciencias Veterinarias
Antimicrobials
Enrofloxacin
Ciprofloxacin
Feathers
Poultry
Residues
description Antibiotics in animal feed are a public health concern. Drug residues could eventually be detected in animal food products intended for human consumption. Our aim was to study the residue depletion of enrofloxacin and its metabolite ciprofloxacin in broiler chicken feathers. A validated HPLC-fluorescence method was used to quantify both compounds in feather samples. Broiler chickens were treated through drinking water with 10 mg Kg-1 d of enrofloxacin for 5 consecutive days. Feather samples were taken from 10 random birds per day until 9 days. Extraction was performed by a liquid/liquid technique. Both fluoroquinolones concentrations were determined by liquid chromatography with fluorescence detection. High levels of enrofloxacin and ciprofloxacin were found in feathers after oral administration and these compounds were detected for 9 days. Feather meal is a potential source of drug residues that can pass through the food chain when contaminated meal is fed to food-producing animals. In the present study enrofloxacin and ciprofloxacin concentrations were 0.20 to 5.46 μg g-1 between 1 to 9 days after final treatment, which means that withdrawal time fit for edible tissues is not adequate to reduce antimicrobial residues in chicken feathers. Further studies to establish a withdrawal time may be useful to avoid that drug residues could result in adverse health consequences like increase in antibiotic resistance.
format Articulo
Articulo
author Marchetti, María Laura
Buchamer, Andrea Verónica
Buldain, Daniel Cornelio
Mestorino, Olga Nora
author_facet Marchetti, María Laura
Buchamer, Andrea Verónica
Buldain, Daniel Cornelio
Mestorino, Olga Nora
author_sort Marchetti, María Laura
title Enrofloxacin and Ciprofloxacin Residues in Broiler Chicken Feathers after Enrofloxacin Oral Administration
title_short Enrofloxacin and Ciprofloxacin Residues in Broiler Chicken Feathers after Enrofloxacin Oral Administration
title_full Enrofloxacin and Ciprofloxacin Residues in Broiler Chicken Feathers after Enrofloxacin Oral Administration
title_fullStr Enrofloxacin and Ciprofloxacin Residues in Broiler Chicken Feathers after Enrofloxacin Oral Administration
title_full_unstemmed Enrofloxacin and Ciprofloxacin Residues in Broiler Chicken Feathers after Enrofloxacin Oral Administration
title_sort enrofloxacin and ciprofloxacin residues in broiler chicken feathers after enrofloxacin oral administration
publishDate 2019
url http://sedici.unlp.edu.ar/handle/10915/153595
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AT buchamerandreaveronica enrofloxacinandciprofloxacinresiduesinbroilerchickenfeathersafterenrofloxacinoraladministration
AT buldaindanielcornelio enrofloxacinandciprofloxacinresiduesinbroilerchickenfeathersafterenrofloxacinoraladministration
AT mestorinoolganora enrofloxacinandciprofloxacinresiduesinbroilerchickenfeathersafterenrofloxacinoraladministration
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