Discovery of hypothalamic hormones controlling pituitary function

A means by which the brain could control the anterior pituitary gland was discovered by B. A. Houssay et al. (1933). In the living toad they found that portal vessels drained blood from a primary capillary plexus in the median eminence (ME) down the pituitary stalk to the sinusoids in the anterior p...

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Autor principal: McCann, Samuel M.
Formato: Articulo Revision
Lenguaje:Inglés
Publicado: 2006
Materias:
Ciencias Médicas
Fisiología
Pituitary gland
Hypothalamic extracts
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/146977
https://pmr.safisiol.org.ar/wp-content/uploads/2022/09/vol1_n9_april.pdf
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SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-146977
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Médicas
Fisiología
Pituitary gland
Hypothalamic extracts
spellingShingle Ciencias Médicas
Fisiología
Pituitary gland
Hypothalamic extracts
McCann, Samuel M.
Discovery of hypothalamic hormones controlling pituitary function
topic_facet Ciencias Médicas
Fisiología
Pituitary gland
Hypothalamic extracts
description A means by which the brain could control the anterior pituitary gland was discovered by B. A. Houssay et al. (1933). In the living toad they found that portal vessels drained blood from a primary capillary plexus in the median eminence (ME) down the pituitary stalk to the sinusoids in the anterior pituitary gland. Popa and Fielding found these vessels in dead animals but believed that the blood flow was upward from the pituitary to the median eminence, a conclusion also reached in the living rabbit by G. W. Harris. Later with Green (1947), he found that the flow was downward in the living rat. Since the blood pressure in the portal vessels is very low, it is likely that, depending on the conditions, flow can be either upward or downward. Additionally, the short portal vessels carry blood from the neural lobe across the intermediate lobe to the anterior lobe, thus delivering neural lobe hormones directly in high concentrations to the anterior lobe of the gland. This fact has been largely neglected.
format Articulo
Revision
author McCann, Samuel M.
author_facet McCann, Samuel M.
author_sort McCann, Samuel M.
title Discovery of hypothalamic hormones controlling pituitary function
title_short Discovery of hypothalamic hormones controlling pituitary function
title_full Discovery of hypothalamic hormones controlling pituitary function
title_fullStr Discovery of hypothalamic hormones controlling pituitary function
title_full_unstemmed Discovery of hypothalamic hormones controlling pituitary function
title_sort discovery of hypothalamic hormones controlling pituitary function
publishDate 2006
url http://sedici.unlp.edu.ar/handle/10915/146977
https://pmr.safisiol.org.ar/wp-content/uploads/2022/09/vol1_n9_april.pdf
work_keys_str_mv AT mccannsamuelm discoveryofhypothalamichormonescontrollingpituitaryfunction
bdutipo_str Repositorios
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