Liver desaturase activities and FA composition in monkeys: effect of a low-protein diet
The aim of the present study was to measure ∆9-, ∆6-, and ∆5-desaturase activities in liver microsomes, as well as phospholipid FA composition of liver and erythrocytes in monkeys fed a control or low-protein diet during the postweaning period. Ten Saimiri sciureus boliviensis (Cebidae) of both sexe...
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| Autores principales: | , , |
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| Formato: | Articulo |
| Lenguaje: | Inglés |
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2003
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| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/145815 |
| Aporte de: |
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I19-R120-10915-145815 |
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| record_format |
dspace |
| institution |
Universidad Nacional de La Plata |
| institution_str |
I-19 |
| repository_str |
R-120 |
| collection |
SEDICI (UNLP) |
| language |
Inglés |
| topic |
Bioquímica Dieta baja en proteínas Liver microsomes Phospholipid FA composition |
| spellingShingle |
Bioquímica Dieta baja en proteínas Liver microsomes Phospholipid FA composition Marín, María Cristina Pucciarelli, Héctor Mario Tacconi de Alaniz, María Josefa Liver desaturase activities and FA composition in monkeys: effect of a low-protein diet |
| topic_facet |
Bioquímica Dieta baja en proteínas Liver microsomes Phospholipid FA composition |
| description |
The aim of the present study was to measure ∆9-, ∆6-, and ∆5-desaturase activities in liver microsomes, as well as phospholipid FA composition of liver and erythrocytes in monkeys fed a control or low-protein diet during the postweaning period. Ten Saimiri sciureus boliviensis (Cebidae) of both sexes were employed; at 12 mon of age they were separated into two groups fed ad libitum on a control or a low-protein diet for 24 mon. Saimiri sciureus had active ∆9, ∆6, and ∆5 liver desaturase enzymes, and these activities were influenced by the diet. A low-protein diet produced a significant reduction in ∆5-desaturation capacity, an increase in ∆9-desaturase activity, and no change in ∆6-desaturase activity (P < 0.05). These changes, evoked by protein deprivation, were reflected in the liver phospholipid FA composition. Increases in the proportion of saturated FA and in monounsaturated oleic acid (18:1n-9) and a decrease in the proportion of PUFA of the n-6 and n-3 series were produced in the animals fed a low-protein diet (P < 0.0001).
Differences between the two dietary groups were less pronounced in the FA composition of erythrocyte phospholipids |
| format |
Articulo Articulo |
| author |
Marín, María Cristina Pucciarelli, Héctor Mario Tacconi de Alaniz, María Josefa |
| author_facet |
Marín, María Cristina Pucciarelli, Héctor Mario Tacconi de Alaniz, María Josefa |
| author_sort |
Marín, María Cristina |
| title |
Liver desaturase activities and FA composition in monkeys: effect of a low-protein diet |
| title_short |
Liver desaturase activities and FA composition in monkeys: effect of a low-protein diet |
| title_full |
Liver desaturase activities and FA composition in monkeys: effect of a low-protein diet |
| title_fullStr |
Liver desaturase activities and FA composition in monkeys: effect of a low-protein diet |
| title_full_unstemmed |
Liver desaturase activities and FA composition in monkeys: effect of a low-protein diet |
| title_sort |
liver desaturase activities and fa composition in monkeys: effect of a low-protein diet |
| publishDate |
2003 |
| url |
http://sedici.unlp.edu.ar/handle/10915/145815 |
| work_keys_str_mv |
AT marinmariacristina liverdesaturaseactivitiesandfacompositioninmonkeyseffectofalowproteindiet AT pucciarellihectormario liverdesaturaseactivitiesandfacompositioninmonkeyseffectofalowproteindiet AT tacconidealanizmariajosefa liverdesaturaseactivitiesandfacompositioninmonkeyseffectofalowproteindiet |
| bdutipo_str |
Repositorios |
| _version_ |
1764820461692125185 |