Ultrastructure of STH cells in the pars distalis of the hypophysis of mice bearing transplanted hepatomas

An electron microscopic analysis was performed on the pars distalis of the hypophysis of mice bearing transplanted hepatomas. Normal mice served as controls. In animals bearing a fast growing as well as in those bearing a slow growing hepatoma, the STH cells presented changes indicating increased re...

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Detalles Bibliográficos
Autores principales: Badrán, Amado F., Nash, R. E., Echave Llanos, Julián Miguel
Formato: Articulo
Lenguaje:Inglés
Publicado: 1971
Materias:
Medicina
Biología
Hypophysis
Mouse
Pars distalis
STH cells
Hepatomas
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/140861
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-140861
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Medicina
Biología
Hypophysis
Mouse
Pars distalis
STH cells
Hepatomas
spellingShingle Medicina
Biología
Hypophysis
Mouse
Pars distalis
STH cells
Hepatomas
Badrán, Amado F.
Nash, R. E.
Echave Llanos, Julián Miguel
Ultrastructure of STH cells in the pars distalis of the hypophysis of mice bearing transplanted hepatomas
topic_facet Medicina
Biología
Hypophysis
Mouse
Pars distalis
STH cells
Hepatomas
description An electron microscopic analysis was performed on the pars distalis of the hypophysis of mice bearing transplanted hepatomas. Normal mice served as controls. In animals bearing a fast growing as well as in those bearing a slow growing hepatoma, the STH cells presented changes indicating increased release and synthesis of its secretory product. These changes can be summarized as follows: 1) Increased number of granuledepleted STH cells which were very irregular in size and shape. 2) Very irregular and sometimes bizarre nuclei. 3) Plasma membranes irregular and convoluted. 4) Increased quantity of endoplasmic reticulum which appeared sometimes dilated and contained material of varying electron density. 5) Abundant, irregular and frequently ramified mitochondria. 6) Hypertrophic Golgi system with increased number of microvesicles. 7) Increased number of large lysosomes of different type. 8) Increased number of fat droplets.
format Articulo
Articulo
author Badrán, Amado F.
Nash, R. E.
Echave Llanos, Julián Miguel
author_facet Badrán, Amado F.
Nash, R. E.
Echave Llanos, Julián Miguel
author_sort Badrán, Amado F.
title Ultrastructure of STH cells in the pars distalis of the hypophysis of mice bearing transplanted hepatomas
title_short Ultrastructure of STH cells in the pars distalis of the hypophysis of mice bearing transplanted hepatomas
title_full Ultrastructure of STH cells in the pars distalis of the hypophysis of mice bearing transplanted hepatomas
title_fullStr Ultrastructure of STH cells in the pars distalis of the hypophysis of mice bearing transplanted hepatomas
title_full_unstemmed Ultrastructure of STH cells in the pars distalis of the hypophysis of mice bearing transplanted hepatomas
title_sort ultrastructure of sth cells in the pars distalis of the hypophysis of mice bearing transplanted hepatomas
publishDate 1971
url http://sedici.unlp.edu.ar/handle/10915/140861
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AT nashre ultrastructureofsthcellsintheparsdistalisofthehypophysisofmicebearingtransplantedhepatomas
AT echavellanosjulianmiguel ultrastructureofsthcellsintheparsdistalisofthehypophysisofmicebearingtransplantedhepatomas
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