Use of the anaphase-telophase test to detect aneugenic compounds : Effects of propionaldehyde and cadmium chloride
Aneuploidy is a numerical chromosomal disorder originated from nondisjunction during cell division (Dellarco 1985). Aneuploid cells exhibit altered chromosome numbers varying from nulisomy (absence of a chromosome pair), monosomy (only one member of a chromosome pair), trisomy (three homologous chro...
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Formato: | Articulo |
Lenguaje: | Inglés |
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1994
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Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/139185 |
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I19-R120-10915-139185 |
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institution |
Universidad Nacional de La Plata |
institution_str |
I-19 |
repository_str |
R-120 |
collection |
SEDICI (UNLP) |
language |
Inglés |
topic |
Veterinaria Aneuploidy Propionaldehyde Cadmium Chloride |
spellingShingle |
Veterinaria Aneuploidy Propionaldehyde Cadmium Chloride Seoane, Analía Isabel Dulout, Fernando Noel Use of the anaphase-telophase test to detect aneugenic compounds : Effects of propionaldehyde and cadmium chloride |
topic_facet |
Veterinaria Aneuploidy Propionaldehyde Cadmium Chloride |
description |
Aneuploidy is a numerical chromosomal disorder originated from nondisjunction during cell division (Dellarco 1985). Aneuploid cells exhibit altered chromosome numbers varying from nulisomy (absence of a chromosome pair), monosomy (only one member of a chromosome pair), trisomy (three homologous chromosomes instead of two), tetrasomy (four homologous chromosomes instead of two), etc. In an aneuploid complement, one or more chromosome pairs can be involved. In human beings aneuploidy is the main cause of pregnant loss, congenital malformation and mental retard (Hook 1983; Epstein 1988). Although the consequences of meiotic non-disjunction are clear, the relation between mitotic non-disjunction and neoplastic transformation susbsists uncertain despite there is increased evidence indicating that it is a significant factor during somatic malignancy development (Kondo 1984; Tsutsui 1983; Cavenee 1983). In addition, aneuploidy is frequently associated with infertility and abortion in domestic livestock (Halnan 1989). <i>(Párrafo extraído del texto a modo de resumen)</i> |
format |
Articulo Articulo |
author |
Seoane, Analía Isabel Dulout, Fernando Noel |
author_facet |
Seoane, Analía Isabel Dulout, Fernando Noel |
author_sort |
Seoane, Analía Isabel |
title |
Use of the anaphase-telophase test to detect aneugenic compounds : Effects of propionaldehyde and cadmium chloride |
title_short |
Use of the anaphase-telophase test to detect aneugenic compounds : Effects of propionaldehyde and cadmium chloride |
title_full |
Use of the anaphase-telophase test to detect aneugenic compounds : Effects of propionaldehyde and cadmium chloride |
title_fullStr |
Use of the anaphase-telophase test to detect aneugenic compounds : Effects of propionaldehyde and cadmium chloride |
title_full_unstemmed |
Use of the anaphase-telophase test to detect aneugenic compounds : Effects of propionaldehyde and cadmium chloride |
title_sort |
use of the anaphase-telophase test to detect aneugenic compounds : effects of propionaldehyde and cadmium chloride |
publishDate |
1994 |
url |
http://sedici.unlp.edu.ar/handle/10915/139185 |
work_keys_str_mv |
AT seoaneanaliaisabel useoftheanaphasetelophasetesttodetectaneugeniccompoundseffectsofpropionaldehydeandcadmiumchloride AT duloutfernandonoel useoftheanaphasetelophasetesttodetectaneugeniccompoundseffectsofpropionaldehydeandcadmiumchloride |
bdutipo_str |
Repositorios |
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1764820457226240002 |