Genomic and phylogenetic analysis of Argentinian Equid Herpesvirus 1 strains

Equid Herpesvirus 1 (EHV-1) has long been causally implicated in the occurrence of abortion, neonatal death, respiratory disease, and neurological disorders in horses. This study analyzed for the first time the characteristics of the genomic section of Argentinian EHV-1 strains and reconstructed the...

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Detalles Bibliográficos
Autores principales: Martín Ocampos, Giselle Paula, Fuentealba, Nadia Analía, Sguazza, Guillermo Hernán, Jones, Leandro Roberto, Cigliano, María Marta, Barbeito, Claudio Gustavo, Galosi, Cecilia Mónica
Formato: Articulo
Lenguaje:Inglés
Publicado: 2009
Materias:
Ciencias Veterinarias
Equid Herpesvirus 1
Argentinian strains
Phylogeny
Evolution
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/132495
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-132495
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Veterinarias
Equid Herpesvirus 1
Argentinian strains
Phylogeny
Evolution
spellingShingle Ciencias Veterinarias
Equid Herpesvirus 1
Argentinian strains
Phylogeny
Evolution
Martín Ocampos, Giselle Paula
Fuentealba, Nadia Analía
Sguazza, Guillermo Hernán
Jones, Leandro Roberto
Cigliano, María Marta
Barbeito, Claudio Gustavo
Galosi, Cecilia Mónica
Genomic and phylogenetic analysis of Argentinian Equid Herpesvirus 1 strains
topic_facet Ciencias Veterinarias
Equid Herpesvirus 1
Argentinian strains
Phylogeny
Evolution
description Equid Herpesvirus 1 (EHV-1) has long been causally implicated in the occurrence of abortion, neonatal death, respiratory disease, and neurological disorders in horses. This study analyzed for the first time the characteristics of the genomic section of Argentinian EHV-1 strains and reconstructed the phylogeny in order to establish their origin. The phylogenetic dataset included 22 Argentinian strains and four additional reference strains isolated in other countries. The intergenic region between ORF 62 and ORF 63 was amplified by PCR and sequenced. The phylogenetic analysis carried out by parsimony algorithms showed that six of the Argentinian strains had the same origin as British and Japanese strains. The mapping of symptoms caused by EHV-1 suggested that neonatal disease developed through convergent evolution, which would constitute an adaptation mechanism of the virus. This study constitutes the first analysis carried out in South-American strains that establishes the phylogenetic relationship between Argentinian strains and rebuilds the evolutionary history of symptoms. This study focuses on a very important aspect of evolution of Herpesviridae infecting perissodactyls and attempts to shed light on the evolution of symptoms, an issue of high clinical interest.
format Articulo
Articulo
author Martín Ocampos, Giselle Paula
Fuentealba, Nadia Analía
Sguazza, Guillermo Hernán
Jones, Leandro Roberto
Cigliano, María Marta
Barbeito, Claudio Gustavo
Galosi, Cecilia Mónica
author_facet Martín Ocampos, Giselle Paula
Fuentealba, Nadia Analía
Sguazza, Guillermo Hernán
Jones, Leandro Roberto
Cigliano, María Marta
Barbeito, Claudio Gustavo
Galosi, Cecilia Mónica
author_sort Martín Ocampos, Giselle Paula
title Genomic and phylogenetic analysis of Argentinian Equid Herpesvirus 1 strains
title_short Genomic and phylogenetic analysis of Argentinian Equid Herpesvirus 1 strains
title_full Genomic and phylogenetic analysis of Argentinian Equid Herpesvirus 1 strains
title_fullStr Genomic and phylogenetic analysis of Argentinian Equid Herpesvirus 1 strains
title_full_unstemmed Genomic and phylogenetic analysis of Argentinian Equid Herpesvirus 1 strains
title_sort genomic and phylogenetic analysis of argentinian equid herpesvirus 1 strains
publishDate 2009
url http://sedici.unlp.edu.ar/handle/10915/132495
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