Mathematical models: a precious tool for research in physiology

The use of mathematical models in science has increased in the last decades, since it is clear that they constitute an essential tool for the progress of experimental research. The main goal of this review is to present to the experimental physiologists some background on the different steps that ar...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Lascano, Elena Catalina, Mattiazzi, Alicia Ramona, Negroni, Jorge Antonio
Formato:	Articulo Revision
Lenguaje:	Inglés
Publicado:	2015
Materias:	Ciencias Médicas mathematical models cardiac myocyte multiscale models intracellular calcium
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/127761 https://pmr.safisiol.org.ar/archive/id/75
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

id	I19-R120-10915-127761
record_format	dspace
institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Ciencias Médicas mathematical models cardiac myocyte multiscale models intracellular calcium
spellingShingle	Ciencias Médicas mathematical models cardiac myocyte multiscale models intracellular calcium Lascano, Elena Catalina Mattiazzi, Alicia Ramona Negroni, Jorge Antonio Mathematical models: a precious tool for research in physiology
topic_facet	Ciencias Médicas mathematical models cardiac myocyte multiscale models intracellular calcium
description	The use of mathematical models in science has increased in the last decades, since it is clear that they constitute an essential tool for the progress of experimental research. The main goal of this review is to present to the experimental physiologists some background on the different steps that are usually followed to develop a model. Probably more important, we aim to provide some basic thoughts to highlight the importance and need of mathematical modeling for scientific discovery and progress. The review also recapitulates the evolution of myocyte and Ca²⁺ handling models, the parallel work done in the interpretation of cardiac force generation, the integration of myocyte and force models into mechano-electric representations, and the construction of multi-scale models by assembling ventricular models with the mathematical descriptions of the circulatory system.
format	Articulo Revision
author	Lascano, Elena Catalina Mattiazzi, Alicia Ramona Negroni, Jorge Antonio
author_facet	Lascano, Elena Catalina Mattiazzi, Alicia Ramona Negroni, Jorge Antonio
author_sort	Lascano, Elena Catalina
title	Mathematical models: a precious tool for research in physiology
title_short	Mathematical models: a precious tool for research in physiology
title_full	Mathematical models: a precious tool for research in physiology
title_fullStr	Mathematical models: a precious tool for research in physiology
title_full_unstemmed	Mathematical models: a precious tool for research in physiology
title_sort	mathematical models: a precious tool for research in physiology
publishDate	2015
url	http://sedici.unlp.edu.ar/handle/10915/127761 https://pmr.safisiol.org.ar/archive/id/75
work_keys_str_mv	AT lascanoelenacatalina mathematicalmodelsaprecioustoolforresearchinphysiology AT mattiazzialiciaramona mathematicalmodelsaprecioustoolforresearchinphysiology AT negronijorgeantonio mathematicalmodelsaprecioustoolforresearchinphysiology
bdutipo_str	Repositorios
_version_	1764820452310515713

Mathematical models: a precious tool for research in physiology

Ejemplares similares