Treatment adherence by personalizing the drug dispensing for diabetic patients in social vulnerable situation

Objectives: We examined the impact of personalizing antidiabetic agents in treatment adherence and in health outcome of socioeconomic vulnerable patients. Methods: We conducted a randomized controlled trial comparing usual “on demand” drug supply from Primary Health Care (PHC) Centers; with a drug...

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Autores principales: Marín, Gustavo Horacio, Risso, Paula, Sbattella, Daniela, Haag, Griselda Octavia
Formato: Articulo
Lenguaje:Inglés
Publicado: 2015
Materias:
Salud
Ciencias Médicas
diabetes
Personalized
Treatment
Adherence
Primary health care
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/127605
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-127605
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Salud
Ciencias Médicas
diabetes
Personalized
Treatment
Adherence
Primary health care
spellingShingle Salud
Ciencias Médicas
diabetes
Personalized
Treatment
Adherence
Primary health care
Marín, Gustavo Horacio
Risso, Paula
Sbattella, Daniela
Haag, Griselda Octavia
Treatment adherence by personalizing the drug dispensing for diabetic patients in social vulnerable situation
topic_facet Salud
Ciencias Médicas
diabetes
Personalized
Treatment
Adherence
Primary health care
description Objectives: We examined the impact of personalizing antidiabetic agents in treatment adherence and in health outcome of socioeconomic vulnerable patients. Methods: We conducted a randomized controlled trial comparing usual “on demand” drug supply from Primary Health Care (PHC) Centers; with a drug dispensing strategy based on a personalized process. 469 patients with type-2 diabetes (DBT) were assigned to either control (CG) or intervention group (IG) assuring a balance in main risk factors. Primary trial endpoint was treatment compliance; however aspects like health events associated to DBT were also evaluated. Results: Adherence to oral agents in CG was 15.57% and 92.09% in IG (p <0.001). Dose omissions represented the most prevalent form of non-adherence. Weight loss was greater in the intervention group than in the control group throughout the study (5.4% in overall weight reduction at study end). Hospital admissions (16.80% vs 10.23% - p <0.01) and coronary heart events (7.37% vs. 3.72% p 0.03) were higher for CG when compared with IG. Conclusions: Diabetes faces the challenge of lifelong treatment. This task is difficult for every patient but is especially hard in social vulnerable situation. Our initiative demonstrate that for the poor and uninsured population, personalizing drug dispensing showed a high level of treatment compliance, and benefits in terms of health consequences associated to diabetes. This experience might be useful for primary care health teams in order to better control social underserved patients, and also for reducing the economical impact for health system caused by complications due to untreated diabetes
format Articulo
Articulo
author Marín, Gustavo Horacio
Risso, Paula
Sbattella, Daniela
Haag, Griselda Octavia
author_facet Marín, Gustavo Horacio
Risso, Paula
Sbattella, Daniela
Haag, Griselda Octavia
author_sort Marín, Gustavo Horacio
title Treatment adherence by personalizing the drug dispensing for diabetic patients in social vulnerable situation
title_short Treatment adherence by personalizing the drug dispensing for diabetic patients in social vulnerable situation
title_full Treatment adherence by personalizing the drug dispensing for diabetic patients in social vulnerable situation
title_fullStr Treatment adherence by personalizing the drug dispensing for diabetic patients in social vulnerable situation
title_full_unstemmed Treatment adherence by personalizing the drug dispensing for diabetic patients in social vulnerable situation
title_sort treatment adherence by personalizing the drug dispensing for diabetic patients in social vulnerable situation
publishDate 2015
url http://sedici.unlp.edu.ar/handle/10915/127605
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AT sbattelladaniela treatmentadherencebypersonalizingthedrugdispensingfordiabeticpatientsinsocialvulnerablesituation
AT haaggriseldaoctavia treatmentadherencebypersonalizingthedrugdispensingfordiabeticpatientsinsocialvulnerablesituation
bdutipo_str Repositorios
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