Output Feedback Linearization of Turbidostats After Time Scaling

Turbidostats are a class of bioreactors gaining interest due to the recent availability of microscale and small-scale devices for characterization and scalingup of the biotechnological systems relevant in the biotech and pharma industries. The goal is to keep cell density constant in continuous oper...

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Detalles Bibliográficos
Autores principales: De Battista, Hernán, Picó-Marco, E., Santos Navarro, Fernando N., Picó, Jesús
Formato: Articulo Preprint
Lenguaje:Inglés
Publicado: 2019
Materias:
Ingeniería Electrónica
Bioreactors
Nonlinear control systems
Output feedback
Adaptive control
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/127276
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-127276
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ingeniería Electrónica
Bioreactors
Nonlinear control systems
Output feedback
Adaptive control
spellingShingle Ingeniería Electrónica
Bioreactors
Nonlinear control systems
Output feedback
Adaptive control
De Battista, Hernán
Picó-Marco, E.
Santos Navarro, Fernando N.
Picó, Jesús
Output Feedback Linearization of Turbidostats After Time Scaling
topic_facet Ingeniería Electrónica
Bioreactors
Nonlinear control systems
Output feedback
Adaptive control
description Turbidostats are a class of bioreactors gaining interest due to the recent availability of microscale and small-scale devices for characterization and scalingup of the biotechnological systems relevant in the biotech and pharma industries. The goal is to keep cell density constant in continuous operation. Thus, the control law, i.e., the substrate feeding strategy, must guarantee global or semiglobal convergence to an equilibrium point. However, their control is difficult due to the uncertain, time varying, and nonlinear nature of the processes involved. In this brief, we propose an adaptive control law that globally stabilizes the desired biomass setpoint. Furthermore, in a certain region of the state space, the controller linearizes the dynamic behavior after some time scaling. By this way, the orbits of the closed-loop system are imposed by the designer. The intrinsic integral action of the gain adaptation rejects the parameter uncertainties. Moreover, the controller implementation only assumes the biomass concentration to be measured. Both the simulated and experimental results show the performance of the controller.
format Articulo
Preprint
author De Battista, Hernán
Picó-Marco, E.
Santos Navarro, Fernando N.
Picó, Jesús
author_facet De Battista, Hernán
Picó-Marco, E.
Santos Navarro, Fernando N.
Picó, Jesús
author_sort De Battista, Hernán
title Output Feedback Linearization of Turbidostats After Time Scaling
title_short Output Feedback Linearization of Turbidostats After Time Scaling
title_full Output Feedback Linearization of Turbidostats After Time Scaling
title_fullStr Output Feedback Linearization of Turbidostats After Time Scaling
title_full_unstemmed Output Feedback Linearization of Turbidostats After Time Scaling
title_sort output feedback linearization of turbidostats after time scaling
publishDate 2019
url http://sedici.unlp.edu.ar/handle/10915/127276
work_keys_str_mv AT debattistahernan outputfeedbacklinearizationofturbidostatsaftertimescaling
AT picomarcoe outputfeedbacklinearizationofturbidostatsaftertimescaling
AT santosnavarrofernandon outputfeedbacklinearizationofturbidostatsaftertimescaling
AT picojesus outputfeedbacklinearizationofturbidostatsaftertimescaling
bdutipo_str Repositorios
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