Multi-response optimization of a green solid-phase extraction for the analysis of heterocyclic aromatic amines in environmental samples

Herein, a method for the multi-response optimization of a green and efficient solid phase extraction (SPE) sample treatment using non-modified multi-walled carbon nanotubes combined with ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) was developed for the quantif...

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Detalles Bibliográficos
Autores principales: Canales, Romina, Mariño Repizo, Leonardo, Reta, Mario Roberto, Cerutti, Soledad
Formato: Articulo Preprint
Lenguaje:Inglés
Publicado: 2020
Materias:
Química
Heterocyclic aromatic amines
Solid-phase extraction
Multi-walled carbon 44 nanotubes
Green certificate
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/127121
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-127121
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Química
Heterocyclic aromatic amines
Solid-phase extraction
Multi-walled carbon 44 nanotubes
Green certificate
spellingShingle Química
Heterocyclic aromatic amines
Solid-phase extraction
Multi-walled carbon 44 nanotubes
Green certificate
Canales, Romina
Mariño Repizo, Leonardo
Reta, Mario Roberto
Cerutti, Soledad
Multi-response optimization of a green solid-phase extraction for the analysis of heterocyclic aromatic amines in environmental samples
topic_facet Química
Heterocyclic aromatic amines
Solid-phase extraction
Multi-walled carbon 44 nanotubes
Green certificate
description Herein, a method for the multi-response optimization of a green and efficient solid phase extraction (SPE) sample treatment using non-modified multi-walled carbon nanotubes combined with ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) was developed for the quantification of ten heterocyclic aromatic amines (HAAs) in river and reservoir surface water samples. The proposed methodology was evaluated by employing experimental designs, which made the approach green. Ultra-trace amounts of HAAs were retained in the SPE cartridge. Then, the analytes were removed from the carbon nanotubes with 0.8 mL of a mixture of acetonitrile/water with 0.1% of formic acid. Under the optimal conditions, linearity was achieved for concentration levels ranging from 0.20 μg L−1 to 500 μg L−1, with regression coefficients (R2) in the range of 0.990 to 0.998. Limits of detection varying from 0.06 μg L−1 and 0.23 μg L−1 were attained, the relative standard deviations (n = 3) varied from 1.7 to 6.4, and the extraction recoveries ranged from 90.6% to 106.0% for all the analytes. The results of the presence of HAAs found in the river samples demonstrated levels ranging from 0.16 μg L−1 to 0.53 μg L−1; meanwhile, in the reservoir samples, the levels were higher, ranging from 0.37 μg L−1 to 0.93 μg L−1. Finally, a comparative discussion was applied to assess the greenness of approaches for the determination of heterocyclic aromatic amines in surface water using the available metrics.
format Articulo
Preprint
author Canales, Romina
Mariño Repizo, Leonardo
Reta, Mario Roberto
Cerutti, Soledad
author_facet Canales, Romina
Mariño Repizo, Leonardo
Reta, Mario Roberto
Cerutti, Soledad
author_sort Canales, Romina
title Multi-response optimization of a green solid-phase extraction for the analysis of heterocyclic aromatic amines in environmental samples
title_short Multi-response optimization of a green solid-phase extraction for the analysis of heterocyclic aromatic amines in environmental samples
title_full Multi-response optimization of a green solid-phase extraction for the analysis of heterocyclic aromatic amines in environmental samples
title_fullStr Multi-response optimization of a green solid-phase extraction for the analysis of heterocyclic aromatic amines in environmental samples
title_full_unstemmed Multi-response optimization of a green solid-phase extraction for the analysis of heterocyclic aromatic amines in environmental samples
title_sort multi-response optimization of a green solid-phase extraction for the analysis of heterocyclic aromatic amines in environmental samples
publishDate 2020
url http://sedici.unlp.edu.ar/handle/10915/127121
work_keys_str_mv AT canalesromina multiresponseoptimizationofagreensolidphaseextractionfortheanalysisofheterocyclicaromaticaminesinenvironmentalsamples
AT marinorepizoleonardo multiresponseoptimizationofagreensolidphaseextractionfortheanalysisofheterocyclicaromaticaminesinenvironmentalsamples
AT retamarioroberto multiresponseoptimizationofagreensolidphaseextractionfortheanalysisofheterocyclicaromaticaminesinenvironmentalsamples
AT ceruttisoledad multiresponseoptimizationofagreensolidphaseextractionfortheanalysisofheterocyclicaromaticaminesinenvironmentalsamples
bdutipo_str Repositorios
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