Oil-In-Water Microemulsions for Thymol Solubilization

Essential oil compounds (EOCs) are molecules with well-known antimicrobial and antipest activity. However, such molecules possess limited solubility in water, making their handling difficult. This work aimed to enhance the distribution of a solid essential oil compound, thymol, using oil-in-water (o...

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Autores principales: Fernández Peña, Laura, Gutiérrez Muro, Sonia, Guzmán, Eduardo, Lucía, Alejandro, Ortega, Francisco, González Rubio, Ramón
Formato: Articulo
Lenguaje:Inglés
Publicado: 2019
Materias:
Ciencias Agrarias
Microemulsions
Essential oil
Phase diagram
Dynamic light scattering
Solubilization
Fluorescence spectroscopy
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/125396
https://www.mdpi.com/2504-5377/3/4/64
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-125396
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Agrarias
Microemulsions
Essential oil
Phase diagram
Dynamic light scattering
Solubilization
Fluorescence spectroscopy
spellingShingle Ciencias Agrarias
Microemulsions
Essential oil
Phase diagram
Dynamic light scattering
Solubilization
Fluorescence spectroscopy
Fernández Peña, Laura
Gutiérrez Muro, Sonia
Guzmán, Eduardo
Lucía, Alejandro
Ortega, Francisco
González Rubio, Ramón
Oil-In-Water Microemulsions for Thymol Solubilization
topic_facet Ciencias Agrarias
Microemulsions
Essential oil
Phase diagram
Dynamic light scattering
Solubilization
Fluorescence spectroscopy
description Essential oil compounds (EOCs) are molecules with well-known antimicrobial and antipest activity. However, such molecules possess limited solubility in water, making their handling difficult. This work aimed to enhance the distribution of a solid essential oil compound, thymol, using oil-in-water (o/w) microemulsions for its solubilization. The use of mixtures formed by an alkyl polyglucoside (APG) and soybean lecithin (SL) allowed for stabilization of the o/w microemulsions in a broad range of compositions, with the total concentration of the mixture of the two surfactants (APG+SL) and the APG:SL ratio both being essential for controlling the nature of the obtained dispersions. The microemulsions obtained using oleic acid as the oil phase and with compositions far from those corresponding to the onset of the emulsion region showed a good efficiency for thymol solubilization. This is an advantage from a stability point of view, as well as for ease of thymol preparation. The present work opens new alternatives for designing eco-sustainable formulations for EOC solubilization, with the possibility of preparing the formulations at the place of use, thereby saving transport costs and reducing the emission of pollutants.
format Articulo
Articulo
author Fernández Peña, Laura
Gutiérrez Muro, Sonia
Guzmán, Eduardo
Lucía, Alejandro
Ortega, Francisco
González Rubio, Ramón
author_facet Fernández Peña, Laura
Gutiérrez Muro, Sonia
Guzmán, Eduardo
Lucía, Alejandro
Ortega, Francisco
González Rubio, Ramón
author_sort Fernández Peña, Laura
title Oil-In-Water Microemulsions for Thymol Solubilization
title_short Oil-In-Water Microemulsions for Thymol Solubilization
title_full Oil-In-Water Microemulsions for Thymol Solubilization
title_fullStr Oil-In-Water Microemulsions for Thymol Solubilization
title_full_unstemmed Oil-In-Water Microemulsions for Thymol Solubilization
title_sort oil-in-water microemulsions for thymol solubilization
publishDate 2019
url http://sedici.unlp.edu.ar/handle/10915/125396
https://www.mdpi.com/2504-5377/3/4/64
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AT luciaalejandro oilinwatermicroemulsionsforthymolsolubilization
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