Noninvasive Approach to Focal Cortical Dysplasias: Clinical, EEG, and Neuroimaging Features

Purpose. The main purpose is to define more accurately the epileptogenic zone (EZ) with noninvasive methods in those patients with MRI diagnosis of focal cortical dysplasia (FCD) and epilepsy who are candidates of epilepsy surgery. Methods. Twenty patients were evaluated prospectively between 2007 a...

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Autores principales: Seifer, Gustavo, Blenkmann, Alejandro, Princich, Juan Pablo, Consalvo, Damián, Papayannis, Cristina, Muravchik, Carlos Horacio, Kochen, Silvia
Formato: Articulo
Lenguaje:Inglés
Publicado: 2012
Materias:
Ingeniería Electrónica
Epilepsia
Neuroimágenes
Imagen por Resonancia Magnética
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/123678
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-123678
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ingeniería Electrónica
Epilepsia
Neuroimágenes
Imagen por Resonancia Magnética
spellingShingle Ingeniería Electrónica
Epilepsia
Neuroimágenes
Imagen por Resonancia Magnética
Seifer, Gustavo
Blenkmann, Alejandro
Princich, Juan Pablo
Consalvo, Damián
Papayannis, Cristina
Muravchik, Carlos Horacio
Kochen, Silvia
Noninvasive Approach to Focal Cortical Dysplasias: Clinical, EEG, and Neuroimaging Features
topic_facet Ingeniería Electrónica
Epilepsia
Neuroimágenes
Imagen por Resonancia Magnética
description Purpose. The main purpose is to define more accurately the epileptogenic zone (EZ) with noninvasive methods in those patients with MRI diagnosis of focal cortical dysplasia (FCD) and epilepsy who are candidates of epilepsy surgery. Methods. Twenty patients were evaluated prospectively between 2007 and 2010 with comprehensive clinical evaluation, video-electroencephalography, diffusion tensor imaging (DTI), and high-resolution EEG to localize the equivalent current dipole (ECD). Key Findings. In 11 cases with white matter asymmetries in DTI the ECDs were located next to lesion on MRI with mean distance of 14.63 millimeters with topographical correlation with the EZ. Significance. We could establish a hypothesis of EZ based on Video-EEG, high-resolution EEG, ECD method, MRI, and DTI. These results are consistent with the hypothesis that the EZ in the FCD is complex and is often larger than visible lesion in MRI.
format Articulo
Articulo
author Seifer, Gustavo
Blenkmann, Alejandro
Princich, Juan Pablo
Consalvo, Damián
Papayannis, Cristina
Muravchik, Carlos Horacio
Kochen, Silvia
author_facet Seifer, Gustavo
Blenkmann, Alejandro
Princich, Juan Pablo
Consalvo, Damián
Papayannis, Cristina
Muravchik, Carlos Horacio
Kochen, Silvia
author_sort Seifer, Gustavo
title Noninvasive Approach to Focal Cortical Dysplasias: Clinical, EEG, and Neuroimaging Features
title_short Noninvasive Approach to Focal Cortical Dysplasias: Clinical, EEG, and Neuroimaging Features
title_full Noninvasive Approach to Focal Cortical Dysplasias: Clinical, EEG, and Neuroimaging Features
title_fullStr Noninvasive Approach to Focal Cortical Dysplasias: Clinical, EEG, and Neuroimaging Features
title_full_unstemmed Noninvasive Approach to Focal Cortical Dysplasias: Clinical, EEG, and Neuroimaging Features
title_sort noninvasive approach to focal cortical dysplasias: clinical, eeg, and neuroimaging features
publishDate 2012
url http://sedici.unlp.edu.ar/handle/10915/123678
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