Enfermedad de sobrecarga lisosomal glicolipídica en un potrillo Morgan

Lysosomal storage diseases are a group of inherited and acquired disorders affecting mammals and birds in which specific substrates accumulate in lysosomes as a result of deficient activity of lysosomal hydrolases. Progressive accumulation of these substrates due to abnormal lysosomal enzymatic degr...

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Detalles Bibliográficos
Autores principales: Loretti, A. P., Lozza, Facundo Andrés, Gimeno, Eduardo Juan, Nordhausen, R. W., Bellamy, P. D., Barr, B. C.
Formato: Articulo Comunicacion
Lenguaje:Inglés
Publicado: 2008
Materias:
Ciencias Veterinarias
Equinos
Lisosomas
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/110604
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-110604
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Veterinarias
Equinos
Lisosomas
spellingShingle Ciencias Veterinarias
Equinos
Lisosomas
Loretti, A. P.
Lozza, Facundo Andrés
Gimeno, Eduardo Juan
Nordhausen, R. W.
Bellamy, P. D.
Barr, B. C.
Enfermedad de sobrecarga lisosomal glicolipídica en un potrillo Morgan
topic_facet Ciencias Veterinarias
Equinos
Lisosomas
description Lysosomal storage diseases are a group of inherited and acquired disorders affecting mammals and birds in which specific substrates accumulate in lysosomes as a result of deficient activity of lysosomal hydrolases. Progressive accumulation of these substrates due to abnormal lysosomal enzymatic degradation results in impairment of cell function and eventually cell death. Multisystemic involvement is common in these disorders so many cell types from a variety of organs and tissues can be affected. Most affected ones would be those with a high turnover of the substrate in question. Neurons are usually involved in these disorders. To date, there are only two published reports of lysosomal storage diseases in horses: a neuronal ceroid lipofuscinosis of presumptive inherited nature, and an acquired mannosidosis associated with the ingestion of the toxic plant Sida carpinifolia. In this case report, the preliminary results of a study about a previously unrecognized lysosomal storage disease in horses are presented.
format Articulo
Comunicacion
author Loretti, A. P.
Lozza, Facundo Andrés
Gimeno, Eduardo Juan
Nordhausen, R. W.
Bellamy, P. D.
Barr, B. C.
author_facet Loretti, A. P.
Lozza, Facundo Andrés
Gimeno, Eduardo Juan
Nordhausen, R. W.
Bellamy, P. D.
Barr, B. C.
author_sort Loretti, A. P.
title Enfermedad de sobrecarga lisosomal glicolipídica en un potrillo Morgan
title_short Enfermedad de sobrecarga lisosomal glicolipídica en un potrillo Morgan
title_full Enfermedad de sobrecarga lisosomal glicolipídica en un potrillo Morgan
title_fullStr Enfermedad de sobrecarga lisosomal glicolipídica en un potrillo Morgan
title_full_unstemmed Enfermedad de sobrecarga lisosomal glicolipídica en un potrillo Morgan
title_sort enfermedad de sobrecarga lisosomal glicolipídica en un potrillo morgan
publishDate 2008
url http://sedici.unlp.edu.ar/handle/10915/110604
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