Are the damaging effects induced by the imazethapyr formulation Pivot® H in Boana pulchella (Anura) reversible upon ceasing exposure?

In the present study, the damage recovery capabilities of Boana pulchella tadpoles after acute exposure (96 h) to 0.39 mg/L concentration of the imazethapyr (IMZT)-based herbicide formulation Pivot® H (25% IMZT LC50 value) were assessed during a period of 7...

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Autores principales:	Pérez Iglesias, Juan Manuel, Natale, Guillermo Sebastián, Soloneski, Sonia María Elsa, Larramendy, Marcelo Luis
Formato:	Articulo
Lenguaje:	Inglés
Publicado:	2018
Materias:	Ciencias Naturales Ciencias Exactas imazethapyr Pivot® H recovery capabilities comet assay micronuclei morphological abnormalities
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/109182 https://www.sciencedirect.com/science/article/abs/pii/S0147651317306814
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

id	I19-R120-10915-109182
record_format	dspace
institution	Universidad Nacional de La Plata
institution_str	I-19
repository_str	R-120
collection	SEDICI (UNLP)
language	Inglés
topic	Ciencias Naturales Ciencias Exactas imazethapyr Pivot® H recovery capabilities comet assay micronuclei morphological abnormalities
spellingShingle	Ciencias Naturales Ciencias Exactas imazethapyr Pivot® H recovery capabilities comet assay micronuclei morphological abnormalities Pérez Iglesias, Juan Manuel Natale, Guillermo Sebastián Soloneski, Sonia María Elsa Larramendy, Marcelo Luis Are the damaging effects induced by the imazethapyr formulation Pivot® H in <i>Boana pulchella</i> (Anura) reversible upon ceasing exposure?
topic_facet	Ciencias Naturales Ciencias Exactas imazethapyr Pivot® H recovery capabilities comet assay micronuclei morphological abnormalities
description	In the present study, the damage recovery capabilities of <i>Boana pulchella</i> tadpoles after acute exposure (96 h) to 0.39 mg/L concentration of the imazethapyr (IMZT)-based herbicide formulation Pivot® H (25% IMZT LC<sub>50</sub> value) were assessed during a period of 7 to −21 days. To appraise the recovery capabilities, frequency of micronuclei (MNs), other nuclear abnormalities and DNA single-strand breaks evaluated by single cell gel electrophoresis assay on circulating blood cells were employed as endpoints for genotoxicity. Growth, development, body mass, and morphological abnormalities were also employed as individual endpoints in the recovery assay. Results demonstrated that IMZT induced sublethal effects at both the individual (i.e., loss of keratodonts) and cytogenetic levels (e.g., increase of MN frequency, other nuclear abnormalities and DNA single-strand breaks). At 11 days of the exposure phase, tadpoles recovered their basal levels of frequency of MNs, other nuclear abnormalities, and comets. However, loss of keratodonts, observed at the end of the exposure period, was present up to 21 days thereafter. Finally, axial abnormalities and delay in development stage were observed only during the postexposure phase in IMZT-exposed tadpoles at 18 and 25 days, respectively and were observed until the end of the experiment. This is the first evidence of use the comet assay as cytogenetic biomarker of genotoxicity in evaluating the recovery capabilities of amphibians in general and also those of <i>B. pulchella</i> after exposure to IMZT.
format	Articulo Articulo
author	Pérez Iglesias, Juan Manuel Natale, Guillermo Sebastián Soloneski, Sonia María Elsa Larramendy, Marcelo Luis
author_facet	Pérez Iglesias, Juan Manuel Natale, Guillermo Sebastián Soloneski, Sonia María Elsa Larramendy, Marcelo Luis
author_sort	Pérez Iglesias, Juan Manuel
title	Are the damaging effects induced by the imazethapyr formulation Pivot® H in <i>Boana pulchella</i> (Anura) reversible upon ceasing exposure?
title_short	Are the damaging effects induced by the imazethapyr formulation Pivot® H in <i>Boana pulchella</i> (Anura) reversible upon ceasing exposure?
title_full	Are the damaging effects induced by the imazethapyr formulation Pivot® H in <i>Boana pulchella</i> (Anura) reversible upon ceasing exposure?
title_fullStr	Are the damaging effects induced by the imazethapyr formulation Pivot® H in <i>Boana pulchella</i> (Anura) reversible upon ceasing exposure?
title_full_unstemmed	Are the damaging effects induced by the imazethapyr formulation Pivot® H in <i>Boana pulchella</i> (Anura) reversible upon ceasing exposure?
title_sort	are the damaging effects induced by the imazethapyr formulation pivot® h in <i>boana pulchella</i> (anura) reversible upon ceasing exposure?
publishDate	2018
url	http://sedici.unlp.edu.ar/handle/10915/109182 https://www.sciencedirect.com/science/article/abs/pii/S0147651317306814
work_keys_str_mv	AT pereziglesiasjuanmanuel arethedamagingeffectsinducedbytheimazethapyrformulationpivothiniboanapulchellaianurareversibleuponceasingexposure AT nataleguillermosebastian arethedamagingeffectsinducedbytheimazethapyrformulationpivothiniboanapulchellaianurareversibleuponceasingexposure AT soloneskisoniamariaelsa arethedamagingeffectsinducedbytheimazethapyrformulationpivothiniboanapulchellaianurareversibleuponceasingexposure AT larramendymarceloluis arethedamagingeffectsinducedbytheimazethapyrformulationpivothiniboanapulchellaianurareversibleuponceasingexposure
bdutipo_str	Repositorios
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Are the damaging effects induced by the imazethapyr formulation Pivot® H in <i>Boana pulchella</i> (Anura) reversible upon ceasing exposure?

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