Human intoxication with paralytic shellfish toxins: Clinical parameters and toxin analysis in plasma and urine

This study reports the data recorded from four patients intoxicated with shellfish during the summer 2002, after consuming ribbed mussels (Aulacomya ater) with paralytic shellfish toxin contents of 8,066 ± 61.37 μg/ 100 gr of tissue. Data associated with clinical variables and paralytic shellfish to...

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Detalles Bibliográficos
Autores principales: García, Carlos, Lagos, Marcelo, Truan, Dominique, Lattes, Karinna, Véjar, Omar, Chamorro, Beatriz, Iglesias, Verónica, Andrinolo, Darío, Lagos, Néstor
Formato: Articulo
Lenguaje:Inglés
Publicado: 2005
Materias:
Ciencias Exactas
paralytic shellfish poisoning
PSP human intoxication
Chilean fjords
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/108926
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-108926
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Exactas
paralytic shellfish poisoning
PSP human intoxication
Chilean fjords
spellingShingle Ciencias Exactas
paralytic shellfish poisoning
PSP human intoxication
Chilean fjords
García, Carlos
Lagos, Marcelo
Truan, Dominique
Lattes, Karinna
Véjar, Omar
Chamorro, Beatriz
Iglesias, Verónica
Andrinolo, Darío
Lagos, Néstor
Human intoxication with paralytic shellfish toxins: Clinical parameters and toxin analysis in plasma and urine
topic_facet Ciencias Exactas
paralytic shellfish poisoning
PSP human intoxication
Chilean fjords
description This study reports the data recorded from four patients intoxicated with shellfish during the summer 2002, after consuming ribbed mussels (Aulacomya ater) with paralytic shellfish toxin contents of 8,066 ± 61.37 μg/ 100 gr of tissue. Data associated with clinical variables and paralytic shellfish toxins analysis in plasma and urine of the intoxicated patients are shown. For this purpose, the evolution of respiratory frequency, arterial blood pressure and heart rate of the poisoned patients were followed and recorded. The clinical treatment to reach a clinically stable condition and return to normal physiological parameters was a combination of hydration with saline solution supplemented with Dobutamine (vasoactive drug), Furosemide (diuretic) and Ranitidine (inhibitor of acid secretion). The physiological condition of patients began to improve after four hours of clinical treatment, and a stable condition was reached between 12 to 24 hours. The HPLC-FLD analysis showed only the GTX3/GTX2 epimers in the blood and urine samples. Also, these epimers were the only paralytic shellfish toxins found in the shellfish extract sample.
format Articulo
Articulo
author García, Carlos
Lagos, Marcelo
Truan, Dominique
Lattes, Karinna
Véjar, Omar
Chamorro, Beatriz
Iglesias, Verónica
Andrinolo, Darío
Lagos, Néstor
author_facet García, Carlos
Lagos, Marcelo
Truan, Dominique
Lattes, Karinna
Véjar, Omar
Chamorro, Beatriz
Iglesias, Verónica
Andrinolo, Darío
Lagos, Néstor
author_sort García, Carlos
title Human intoxication with paralytic shellfish toxins: Clinical parameters and toxin analysis in plasma and urine
title_short Human intoxication with paralytic shellfish toxins: Clinical parameters and toxin analysis in plasma and urine
title_full Human intoxication with paralytic shellfish toxins: Clinical parameters and toxin analysis in plasma and urine
title_fullStr Human intoxication with paralytic shellfish toxins: Clinical parameters and toxin analysis in plasma and urine
title_full_unstemmed Human intoxication with paralytic shellfish toxins: Clinical parameters and toxin analysis in plasma and urine
title_sort human intoxication with paralytic shellfish toxins: clinical parameters and toxin analysis in plasma and urine
publishDate 2005
url http://sedici.unlp.edu.ar/handle/10915/108926
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