An analysis of k-mer frequency features with SVM and CNN for viral subtyping classification

Viral subtyping classification is very relevant for the appropriate diagnosis and treatment of illnesses. The most used tools are based on alignment-based methods, nevertheless, they are becoming too slow due to the increase of genomic data; for that reason, alignmentfree methods have emerged as an...

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Detalles Bibliográficos
Autor principal: Machaca Arceda, Vicente Enrique
Formato: Articulo
Lenguaje:Inglés
Publicado: 2020
Materias:
CNN
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/108009
Aporte de:
id I19-R120-10915-108009
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Ciencias Informáticas
CNN
Genome
Viral subtyping
k-mer
Kameris
Castor
ML-DSP
Genoma
Subtipos de virus
spellingShingle Ciencias Informáticas
CNN
Genome
Viral subtyping
k-mer
Kameris
Castor
ML-DSP
Genoma
Subtipos de virus
Machaca Arceda, Vicente Enrique
An analysis of k-mer frequency features with SVM and CNN for viral subtyping classification
topic_facet Ciencias Informáticas
CNN
Genome
Viral subtyping
k-mer
Kameris
Castor
ML-DSP
Genoma
Subtipos de virus
description Viral subtyping classification is very relevant for the appropriate diagnosis and treatment of illnesses. The most used tools are based on alignment-based methods, nevertheless, they are becoming too slow due to the increase of genomic data; for that reason, alignmentfree methods have emerged as an alternative. In this work, we analyzed four alignment-free algorithms: two methods use k-mer frequencies (Kameris and Castor-KRFE); the third method used a frequency chaos game representation of a DNA with CNNs; and the last one processes DNA sequences as a digital signal (ML-DSP). From the comparison, Kameris and Castor-KRFE outperformed the rest, followed by the method based on CNNs.
format Articulo
Articulo
author Machaca Arceda, Vicente Enrique
author_facet Machaca Arceda, Vicente Enrique
author_sort Machaca Arceda, Vicente Enrique
title An analysis of k-mer frequency features with SVM and CNN for viral subtyping classification
title_short An analysis of k-mer frequency features with SVM and CNN for viral subtyping classification
title_full An analysis of k-mer frequency features with SVM and CNN for viral subtyping classification
title_fullStr An analysis of k-mer frequency features with SVM and CNN for viral subtyping classification
title_full_unstemmed An analysis of k-mer frequency features with SVM and CNN for viral subtyping classification
title_sort analysis of k-mer frequency features with svm and cnn for viral subtyping classification
publishDate 2020
url http://sedici.unlp.edu.ar/handle/10915/108009
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