Genetic and phenotypic variability of iris color in Buenos Aires population
The aim of this work was to describe the phenotypic and genotypic variability related to iris color for the population of Buenos Aires province (Argentina), and to assess the usefulness of current methods of analysis for this country. We studied five Single Nucleotide Polymorphisms (SNPs) included i...
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| Autores principales: | , , , |
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| Formato: | Articulo |
| Lenguaje: | Inglés |
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2018
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| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/107886 http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC5901501&blobtype=pdf |
| Aporte de: |
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I19-R120-10915-107886 |
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dspace |
| institution |
Universidad Nacional de La Plata |
| institution_str |
I-19 |
| repository_str |
R-120 |
| collection |
SEDICI (UNLP) |
| language |
Inglés |
| topic |
Ciencias Exactas Population genetics iris color forensic genetics phenotype determination Argentinian population |
| spellingShingle |
Ciencias Exactas Population genetics iris color forensic genetics phenotype determination Argentinian population Hohl, Diana María Bezus, Brenda Ratowiecki, Julia Catanesi, Cecilia Inés Genetic and phenotypic variability of iris color in Buenos Aires population |
| topic_facet |
Ciencias Exactas Population genetics iris color forensic genetics phenotype determination Argentinian population |
| description |
The aim of this work was to describe the phenotypic and genotypic variability related to iris color for the population of Buenos Aires province (Argentina), and to assess the usefulness of current methods of analysis for this country. We studied five Single Nucleotide Polymorphisms (SNPs) included in the IrisPlex kit, in 118 individuals, and we quantified eye color with Digital Iris Analysis Tool. The markers fit Hardy-Weinberg equilibrium for the whole sample, but not for rs12913832 within the group of brown eyes (LR=8.429; p=0.004). We found a remarkable association of <i>HERC2</i> rs12913832 GG with blue color (p < 0.01) but the other markers did not show any association with iris color. The results for the Buenos Aires population differ from those of other populations of the world for these polymorphisms (p < 0,01). The differences we found might respond to the admixed ethnic composition of Argentina; therefore, methods of analysis used in European populations should be carefully applied when studying the population of Argentina. These findings reaffirm the importance of this investigation in the Argentinian population for people identification based on iris color. |
| format |
Articulo Articulo |
| author |
Hohl, Diana María Bezus, Brenda Ratowiecki, Julia Catanesi, Cecilia Inés |
| author_facet |
Hohl, Diana María Bezus, Brenda Ratowiecki, Julia Catanesi, Cecilia Inés |
| author_sort |
Hohl, Diana María |
| title |
Genetic and phenotypic variability of iris color in Buenos Aires population |
| title_short |
Genetic and phenotypic variability of iris color in Buenos Aires population |
| title_full |
Genetic and phenotypic variability of iris color in Buenos Aires population |
| title_fullStr |
Genetic and phenotypic variability of iris color in Buenos Aires population |
| title_full_unstemmed |
Genetic and phenotypic variability of iris color in Buenos Aires population |
| title_sort |
genetic and phenotypic variability of iris color in buenos aires population |
| publishDate |
2018 |
| url |
http://sedici.unlp.edu.ar/handle/10915/107886 http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC5901501&blobtype=pdf |
| work_keys_str_mv |
AT hohldianamaria geneticandphenotypicvariabilityofiriscolorinbuenosairespopulation AT bezusbrenda geneticandphenotypicvariabilityofiriscolorinbuenosairespopulation AT ratowieckijulia geneticandphenotypicvariabilityofiriscolorinbuenosairespopulation AT catanesiceciliaines geneticandphenotypicvariabilityofiriscolorinbuenosairespopulation |
| bdutipo_str |
Repositorios |
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1764820443741552642 |