Fine-scale genomic analyses of admixed individuals reveal unrecognized genetic ancestry components in Argentina

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Similarly to other populations across the Americas, Argentinean populations trace back their genetic ancestry into African, European and Native American ancestors, reflecting a complex demographic history with multiple migration and admixture events in pre- and postcolonial times. However, little is...

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Autores principales: Luisi, Pierre, García, Angelina, Berros, Juan Manuel, Motti, Josefina María Brenda, Demarchi, Darío Alfredo, Alfaro Gómez, Emma Laura, Aquilano, Eliana, Argüelles, Carina Francisca, Avena, Sergio Alejandro, Bailliet, Graciela, Beltramo, Julieta, Bravi, Claudio Marcelo, Cuello, Mariela Vanesa, Dejean, Cristina Beatriz, Dipierri, José Edgardo, Jurado Medina, Laura Smeldy, Lanata, José Luis, Muzzio, Marina, Parolín, María Laura, Pauro, Maia, Paz Sepúlveda, Paula B., Rodríguez Golpe, Daniela, Santos, María Rita, Schwab, Marisol Elisabet, Silvero, Zubrzycki, Jeremias, Ramallo, Virginia, Dopazo, Hernán
Formato: Articulo
Lenguaje:Inglés
Publicado: 2020
Materias:
Biología
Genetic ancestry
Argentina
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/106932
http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC7365470&blobtype=pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-106932
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Biología
Genetic ancestry
Argentina
spellingShingle Biología
Genetic ancestry
Argentina
Luisi, Pierre
García, Angelina
Berros, Juan Manuel
Motti, Josefina María Brenda
Demarchi, Darío Alfredo
Alfaro Gómez, Emma Laura
Aquilano, Eliana
Argüelles, Carina Francisca
Avena, Sergio Alejandro
Bailliet, Graciela
Beltramo, Julieta
Bravi, Claudio Marcelo
Cuello, Mariela Vanesa
Dejean, Cristina Beatriz
Dipierri, José Edgardo
Jurado Medina, Laura Smeldy
Lanata, José Luis
Muzzio, Marina
Parolín, María Laura
Pauro, Maia
Paz Sepúlveda, Paula B.
Rodríguez Golpe, Daniela
Santos, María Rita
Schwab, Marisol Elisabet
Silvero,
Zubrzycki, Jeremias
Ramallo, Virginia
Dopazo, Hernán
Fine-scale genomic analyses of admixed individuals reveal unrecognized genetic ancestry components in Argentina
topic_facet Biología
Genetic ancestry
Argentina
description Similarly to other populations across the Americas, Argentinean populations trace back their genetic ancestry into African, European and Native American ancestors, reflecting a complex demographic history with multiple migration and admixture events in pre- and postcolonial times. However, little is known about the sub-continental origins of these three main ancestries. We present new high-throughput genotyping data for 87 admixed individuals across Argentina. This data was combined to previously published data for admixed individuals in the region and then compared to different reference panels specifically built to perform population structure analyses at a sub-continental level. Concerning the Native American ancestry, we could identify four Native American components segregating in modern Argentinean populations. Three of them are also found in modern South American populations and are specifically represented in Central Andes, Central Chile/Patagonia, and Subtropical and Tropical Forests geographic areas. The fourth component might be specific to the Central Western region of Argentina, and it is not well represented in any genomic data from the literature. As for the European and African ancestries, we confirmed previous results about origins from Southern Europe, Western and Central Western Africa, and we provide evidences for the presence of Northern European and Eastern African ancestries.
format Articulo
Articulo
author Luisi, Pierre
García, Angelina
Berros, Juan Manuel
Motti, Josefina María Brenda
Demarchi, Darío Alfredo
Alfaro Gómez, Emma Laura
Aquilano, Eliana
Argüelles, Carina Francisca
Avena, Sergio Alejandro
Bailliet, Graciela
Beltramo, Julieta
Bravi, Claudio Marcelo
Cuello, Mariela Vanesa
Dejean, Cristina Beatriz
Dipierri, José Edgardo
Jurado Medina, Laura Smeldy
Lanata, José Luis
Muzzio, Marina
Parolín, María Laura
Pauro, Maia
Paz Sepúlveda, Paula B.
Rodríguez Golpe, Daniela
Santos, María Rita
Schwab, Marisol Elisabet
Silvero,
Zubrzycki, Jeremias
Ramallo, Virginia
Dopazo, Hernán
author_facet Luisi, Pierre
García, Angelina
Berros, Juan Manuel
Motti, Josefina María Brenda
Demarchi, Darío Alfredo
Alfaro Gómez, Emma Laura
Aquilano, Eliana
Argüelles, Carina Francisca
Avena, Sergio Alejandro
Bailliet, Graciela
Beltramo, Julieta
Bravi, Claudio Marcelo
Cuello, Mariela Vanesa
Dejean, Cristina Beatriz
Dipierri, José Edgardo
Jurado Medina, Laura Smeldy
Lanata, José Luis
Muzzio, Marina
Parolín, María Laura
Pauro, Maia
Paz Sepúlveda, Paula B.
Rodríguez Golpe, Daniela
Santos, María Rita
Schwab, Marisol Elisabet
Silvero,
Zubrzycki, Jeremias
Ramallo, Virginia
Dopazo, Hernán
author_sort Luisi, Pierre
title Fine-scale genomic analyses of admixed individuals reveal unrecognized genetic ancestry components in Argentina
title_short Fine-scale genomic analyses of admixed individuals reveal unrecognized genetic ancestry components in Argentina
title_full Fine-scale genomic analyses of admixed individuals reveal unrecognized genetic ancestry components in Argentina
title_fullStr Fine-scale genomic analyses of admixed individuals reveal unrecognized genetic ancestry components in Argentina
title_full_unstemmed Fine-scale genomic analyses of admixed individuals reveal unrecognized genetic ancestry components in Argentina
title_sort fine-scale genomic analyses of admixed individuals reveal unrecognized genetic ancestry components in argentina
publishDate 2020
url http://sedici.unlp.edu.ar/handle/10915/106932
http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC7365470&blobtype=pdf
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